ARTICLE IN PRESSJID:JACL[mNS:June2,2023,16:4Journal of Clinical Lipidology(2023)000,1-24Journal ofClinicalLipidologyClinical PerspectiveNutrition interventions for adults withdyslipidemia:A Clinical Perspective from theNational Lipid AssociationCarol F.Kirkpatrick,PhD,RDN,CLS,FNLA1,Geeta Sikand,MA,RDN,CDE,CLS,FAND,FNLA1,Kristina S.Petersen,PhD,APD,FAHA,Cheryl A.M.Anderson,PhD,MPH,FAHA,Karen E.Aspry,MD,MS,FNLA,Julie P.Bolick,MS,RDN,CD,CLS,FNLA,Penny M.Kris-Etherton,PhD,RDN,CLS,FAHA,FASN,FNLA#,Kevin C.Maki,PhD,CLS,FACN,FNLA,FTOS#*Midwest Biomedical Research,Addison,IL,USA;Kasiska Division of Health Sciences,Idaho State University,Pocatello,ID,USA;University of California Irvine Heart Disease Prevention Program,Irvine,CA,USA:Department of NutritionalSciences,Texas Tech University,Lubbock,TX,USA:Herbert Wertheim School of Public Health and Human LongevityScience,University of Califomia San Diego,La Jolla,CA,USA;Lifespan Cardiovascular Institute,and Alpert MedicalSchool,Brown University,Providence,RI,USA:Private Practice Dietitian,Sandy,UT,USA:Department of NutritionalSciences,The Pennsylvania State University,University Park,PA,USA:Indiana University School of PublicHealth-Bloomington,Bloomington,IN,USAKEY WORDSAbstract:Lifestyle habits can have a profound impact on atherosclerotic cardiovascular disease(AS.Lifestyle habits:CVD)risk.The National Lipid Association previously published recommendations for lifestyle therapiesASCVD;to manage dyslipidemia.This Clinical Perspective provides an update with a focus on nutrition interven-Dyslipidemia:tions for the three most common dyslipidemias in adults:1)low-density lipoprotein cholesterol (LDL-C)Nutrition interventions;elevation;2)triglyceride(TG)elevation,including severe hypertriglyceridemia with chylomicronemia;Low-density lipoproteinand 3)combined dyslipidemia,with elevations in both LDL-C and TG levels.Lowering LDL-C and non-cholesterol (LDL-C);high-density lipoprotein cholesterol are the primary objectives for reducing ASCVD risk.With severeTriglyceride(TG)TG elevation(500 mg/dL),the primary objective is to prevent pancreatitis and ASCVD risk reductionelevation;is secondary.Nutrition interventions that lower LDL-C levels include reducing cholesterol-raising fattyObesityacids and dietary cholesterol,as well as increasing intakes of unsaturated fatty acids,plant proteins,vis-*Endorsed by the American Society for Preventive Cardiology and Preventive Cardiovascular Nurses Association.Corresponding author.E-mail address:kmaki@mbclinicalresearch.com (K.C.Maki).Submitted May 18,2023.Accepted for publication May 19,2023ICo-first authorsCo-senior authors1933-2874/2023 National Lipid Association.Published by Elsevier Inc.This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0)https:/doi.arg/10.1016.jacl.2023.05.099Please cite this article as:Kirkpatrick et al,Nutrition interventions for adults with dyslipidemia:A clinical perspective from the national lipi
