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Journal of Ultrasoundhttp5/doi.org/10.1007/s40477-023-00788-2ORIGINAL PAPERSIUMB recommendations on the use of ultrasound in neoplasticlesions of the gallbladder and extrahepatic biliary tractllario de Sio'.Mirko D'Onofrio2.Paoletta Mirk3.Michele Bertolotto.Kateryna Priadko.Cosima Schiavones.Vito Cantisanis.Giovanni lannetti.Gianfranco Vallone.Gianpaolo Vidili.The SIUMB experts committeeReceived:25 January 2023/Accepted:31 March 2023©The Author(s)2023AbstractExtrahepatic biliary tract and gallbladder neoplastic lesions are relatively rare and hence are often underrepresented in thegeneral clinical recommendations for the routine use of ultrasound(US).Dictated by the necessity of updated summarizedreview of current literature to guide clinicians,this paper represents an updated position of the Italian Society of Ultrasoundin Medicine and Biology (SIUMB)on the use of US and contrast-enhanced ultrasound(CEUS)in extrahepatic biliarytract and gallbladder neoplastic lesions such as extrahepatic cholangiocarcinoma,gallbladder adenocarcinoma,gallbladderadenomyomatosis,dense bile with polypoid-like appearance and gallbladder polyps.Keywords Ultrasound.Neoplastic lesions.Extrahepatic biliary tract.Gallbladder.Contrast-enhanced ultrasoundAbbreviationsESGEEuropean Society of GastrointestinalCEUSContrast-enhanced ultrasoundEndoscopyCTComputed tomographyMRIMagnetic resonance imagingEAESEuropean Association of Endoscopic SurgeryRASRokitansky-Aschoff's sinuseEFISDSEuropean Federation International Society forSIUMBItalian Society of Ultrasound in Medicine andDigestive SurgeryBiologyEFSUMBEuropean Federation of Societies for Ultra-PPVPositive predictive valuesound in Medicine and BiologyNPVNegative predictive valueESGAREuropean Society of Gastrointestinal andUCAUltrasound contrast agentAbdominal RadiologyUSUltrasoundThe SIUMB experts'committee members are listed inAcknowledgements.☒Kateryna Priadko6Department of Radiological Sciences,Policlinico Umberto I,Kateryna.Priadko@unicampania.itUniversity La Sapienza,Rome,ItalyDepartment of Hepatogastroenterology.Universita DegliDepartment of Internistic Ultrasound,Civil HospitalStudi Della Campania"Luigi Vanvitelli",Naples,Italyof Pescara,Pescara,Italy8Department of Radiology,G.B.Rossi Hospital,UniversityDepartment of Medicine and Health Sciences,"V.Tiberio"of the University of Molise.Molise.Italyof Verona,Verona,Italy9Department of Radiology.Catholic University of the SacredDepartment of Medical,Surgical and Experimental Sciences,University of Sassari,Sassari,ItalyHeart-Fondazione Policlinico A.Gemelli,Rome,ItalyDepartment of Radiology,University of Trieste,Ospedale diCattinara,Trieste,ItalyUnit of Internistic Ultrasound,Department of Medicineand Science of Aging."G.d'Annunzio"University.Chieti.ItalyPublished online:05 May 2023Springer