價Check for updatesReceived:12 April 2023 Accepted:15 April 2023D0k:10.1111/aa5.14262CLINICAL PRACTICE GUIDELINE@ctascanahsieogcaNew-onset atrial fibrillation in critically ill adult patients-anSSAl clinical practice guidelineAnne Sofie Andreasen1 Mik Wetterslev2 Martin Ingi Sigurdsson34Jeppe Bove5 Jesper Kjaergaard5 Tayyba Naz Aslam78 Kati JarvelaMette Poulsen10 Lina De Geer11 Arnav Agarwal12.13.14Maj-Brit Norregaard Kjaer2 Morten Hylander Moller2.15Department of Intensive Care,Copenhagen University Hospital-Herlev.Herlev,Denmark2Department of Intensive Care,Copenhagen University Hospital-Rigshospitalet,Copenhagen,Denmark3Division of Anesthesia and Intensive Care Medicine,Landspitali-The National University Hospital of kceland,Reykjavik,IcelandFaculty of Medicine,University of Iceland,Reykjavik,lcelandSDepartment of Anaesthesia and Intensive Care.Odense University Hospital,Odense,DenmarkDepartment of Cardiology.Copenhagen University Hospital-Rigshospitalet.Copenhagen,DenmarkDepartment of Research and Development.Division of Emergencies and Critical Care.Oslo University Hospital.Oslo.NorwayInstitute of Clinical Medicine,University of Oslo,Oslo,NorwayHeart Hospital Tampere University Hospital Tampere.FinlandDepartment of Intensive Care,Aarhus University Hospital,Aarhus,DenmarkDepartment of Anaesthesiology and Intensive Care,and Department of Biomedical and Clinical Scences,Linkoping University.Linkoping.SwedenDivision of General Internal Medicine,Department of Medicine.McMaster University.Hamilton,Ontario,Canada13Department of Heat Research Methods,Evidence and Impact McMaster University.Hamilton Ontario.CanadaMAGIC Evidence Ecosystem Foundation,Norway4Department of Cinical Medicine.University of Copenhagen,Copenhagen.DenmarkCorrespondenceMorten Hylander Moller,Department ofAbstractIntensive Care,Copenhagen UniversityBackground:Acute or new-onset atrial fibrillation (NOAF)is the most common car-Hospital Rigshospitalet,Blegdamsvej 7,DK-2100 Copenhagen,Denmark.diac arrhythmia in critically ill adult patients,and observational data suggests thatEmail:mortenhylander@gmail.comNOAF is associated to adverse outcomes.Methods:We prepared this guideline according to the Grading of RecommendationsAssessment,Development and Evaluation methodology.We posed the following clin-ical questions:(1)what is the better first-line pharmacological agent for the treatmentof NOAF in critically ill adult patients?,(2)should we use direct current(DC)cardioversion in critically ill adult patients with NOAF and hemodynamic insta-bility caused by atrial fibrillation?,(3)should we use anticoagulant therapy in criticallyill adult patients with NOAF?,and (4)should critically ill adult patients with NOAFThis guideline has been prepared in collaboration with MAGIC and isavailable online.This is an open access artide under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License,which permits use and distribution in anymedium,provided the original work is properly