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2023澳大利亚和新西兰共识指南:儿童新诊断免疫性血小板减少症

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2023澳大利亚和新西兰共识指南:儿童新诊断免疫性血小板减少症-医知素材库
2023澳大利亚和新西兰共识指南:儿童新诊断免疫性血小板减少症
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Journal of Paediatrics andChild Healthdot10.1111Ujpc.16395POSITION PAPERAustralian and New Zealand consensus guideline for paediatricnewly diagnosed immune thrombocytopaenia endorsedby Australian New Zealand Children's Haematologyand Oncology GroupVanessa Verissimo,12 Tina Carter,2.34 Helen Wright,5.6 Jeremy Robertson,7 Michael Osborn,?Peter Bradbeer,1 Vanaja Sabesan,Ben Saxon,2.Pasquale Barbaro,4 Gemma Crighton,Janis Chamberlain,Silvia Zheng17 and Kate Freeman'sHaematology Department,3Haematology and Oncology Department,General Paediatric Department,Perth Children's Hospital,Haematology/OncologyResearch,Telethon Kids Institute,Rural Clinical School,University of Western Australia,Perth,Department of Haematology,PathWest,Nedlands,WesternAustralia,Department of Haematology,The Wesley Hospital,Department of Haematology,University of Queensland,"Department Haematology andOncology,Queensland Children's Hospital,Brisbane,"Department of Paediatrics,Townsville Hospital and Health Service,Townsville,Queensland,Consultant Haematologist/Paediatric Oncologist,Womens and Childrens Hospital,12Department of Haematology/Oncology,Women's and Children'sHospital,Paediatric Education,University of Adelaide,Adelaide,South Australia,Department of Haematology,Royal Children's Hospital,Melboure,Victora,"Children's Cancer and Haematology Service,John Hunter Children's Hospital University of Newcastle,Newcastle,Department of Haematology,St.George Hospital,Sydney,New South Wales,Department of General Paediatrics,Royal Darwin Hospital,Darwin,Northem Territory,Australia andDepartment of Haematology,Starship Blood and Cancer Centre,Auckland,NewZealandIn children,the majority of cases are self-limiting and thus many paediatric patients can be managed conservatively with minimal complications.Thisvaries considerably compared to adult newly diagnosed immune thrombocytopaenia(NDITP)where,in most cases,thrombocytopaenia persists withhigher risk of moderate to severe bleeding complications.In the past decade,local and international guidelines have emerged to supportapproaches to the investigation and management of NDITP,with a focus primarily on adult immune thrombocytopaenia(ITP).International consen-sus guidelines on paediatric NDITP have been developed,however gaps remain,and approaches vary between North American,Asia,Europe andthe UK.There are no current Australian or New Zealand paediatric ITP guidelines readily available,rather differing guidelines for each state,territoryor island.These inconsistencies cause uncertainty for patients,families and physicians managing cases.Subsequently,physicians,including paediat-ric haematologists and general paediatricians,have come together to provide a consensus approach guideline specific to paediatric NDITP forAustralian or New Zealand.Persistent or chronic paediatric ITP remains a complex and separate entity and are not discussed here.Key words:bleeding risk;immune thrombocytopaenia;management;paediatrics;treatment.Immune thrombocyto
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