medicinaMDPIReviewInternational Consensus on Definition of Mild-to-ModerateUlcerative Colitis Disease Activity in Adult PatientsBenedicte Caron1,Vipul Jairath 2,3,Ferdinando D'Amico 4,5,Sameer Al Awadhi 6,Axel Dignass 7,Ailsa L.Hart8Taku Kobayashi9,Paulo Gustavo Kotze 10,Fernando Magro 11,12,13,Britta Siegmund 14,15,Kristine Paridaens 16,Silvio Danese 4,*and Laurent Peyrin-Biroulet11Department of Gastroenterology and Inserm NGERE U1256,Nancy University Hospital,University of Lorraine,54500 Vandoeuvre-les-Nancy,France2Department of Medicine,Western University,London,ON N6A 3K7,Canada3Department of Epidemiology and Biostatistics,Western University,London,ON N6A 3K7,Canada4Gastroenterology and Endoscopy,IRCCS Ospedale San Raffaele and University Vita-SaluteSan Raffaele,20132 Milan,Italy5Department of Biomedical Sciences,Humanitas University,Pieve Emanuele,20090 Milan,Italy6Gastroenterology Division,Rashid Hospital,Dubai Health Authority,Dubai 003206,United Arab Emirates7Department of Medicine I,Agaplesion Markus Hospital,Goethe-University,60431 Frankfurt am Main,Germany8Inflammatory Bowel Disease Unit,St.Mark's Hospital,Harrow HA1 3UJ,UK9Center for Advanced IBD Research and Treatment,Kitasato University Kitasato Institute Hospital,Tokyo 108-8642,Japan10IBD Outpatient Clinics,Colorectal Surgery Unit,Pontificia UniversidadeCatolica do Parana(PUCPR),Curitiba 80215-901,Brazil11Unit of Pharmacology and Therapeutics,Department of Biomedicine,Faculty of Medicine,University ofPorto,4200319 Porto,PortugalDepartment of Clinical Pharmacology,Sio Joo University Hospital Center(CHUSD),4200319 Porto,Portugal13Center for Health Technology and Services Research(CINTESIS),4200319 Porto,PortugalCharite-Universitatsmedizin Berlin,Corporate Member of Freie Universitat Berlin,Humboldt-Universitat zuCitation:Caron,B.:Jairath,V;Berlin and Berlin Institute of Health,10117 Berlin,GermanyD'Amico,E;AI Awadhi,S;Dignass,15Department of Gastroenterology,Rheumatology and Infectious Disease,Campus Benjamin Franklin,A.;Hart,A.L;Kobayashi,T;Kotze10117 Berlin,GermanyPG.;Magro,F;Siegmund,B.;et al6Ferring International Center S.A.Ch.Dela Vergognausaz 50,1162 Saint-Prex,SwitzerlandInternational Consensus onCorrespondence:sdanesehotmail.comDefinition of Mild-to-ModerateUlcerative Colitis Disease Activ ity inAbstract:Background and Objectives:At present,there is no consensus definition of mild-to-moderateAdult Patients.Medicim 2023,59,183.disease activity in patients with ulcerative colitis.The objective of the present study was to establishhttps://doiorg/103390/a reliable definition of mild-to-moderate disease activity in adult patients with ulcerative colitismedicina59010183Materials and Methods:Twelve physicians from around the world participated in a virtual consensusAcademie Editors:Ludovicomeeting on 26 September 2022.All the physicians had expertise in the diagnosis and treatmentAbenavoli and Marcello Candelliof inflammatory bowel disease.After a systematic review of the literature
