Can J Anesth/J Can Anesthhttps::/loi.org/10.1007s12630-023-02431-4SPECIAL ARTICLEA brain-based definition of death and criteria for itsdetermination after arrest of circulation or neurologic functionin Canada:a 2023 clinical practice guidelineSamD.Shemie,MDD·Lindsay C.Wilson,MHA·Laura Hornby.,MSc·John Basmaji,.MD·Andrew J.Baker,MD Cecile M.Bensimon,PhD.Jennifer A.Chandler,LLM.Michael Chasse,MD,PhD.Rosanne Dawson,LLB·Sonny Dhanani,MD·Owen T.Mooney,MD·Aimee J.Sarti,MD,Med·Christy Simpson,PhD·Jeanne Teitelbaum,MD·Sylvia Torrance,.BSc·J.Gordon Boyd,.MD,PhD·Joanne Brennan,RN·Heather Brewster·Robert Carignan·Kirk J.Dawe,NP,MN·Christopher J.Doig,MD,MSc.Kennedy Elliott-Pohl,BSKin Teneille E.Gofton,MD,MSc.Michael Hartwick,MD,Med·Andrew Healey,MD·Kimia Honarmand,MD,MSc·Karen Hornby,MSc·George Isac,MD·Aly Kanji,,MD,MSe·Joann Kawchuk,MD·Jennifer A.Klowak,MD,MSc·Andreas H.Kramer,MD,MSc.Julie Kromm,MD.Allana E.LeBlanc,RN,MScN.Katarina Lee-Ameduri,,JD,MA·Laurie A.Lee,NP,MN·Murdoch Leeies,MD,MSc·Ariane Lewis,.MD·Alex Manara,FRCP,FFICM.Shauna Matheson,RN,BScN.Nicole K.A.McKinnon,MD,PhD.Nicholas Murphy,PhD.Joel Neves Briard,MD,Msc.Thaddeus M.Pope,JD,PhD Mypinder S.Sekhon,MD.Jai Jai S.Shanker,MD,MSc.Gurmeet Singh,MD,MSc.Jeffrey Singh,MD,MSc.Marat Slessarev,MD,PhD.Karim Soliman,.MD·Stephanie Sutherland,.PhD·Matthew J.Weiss,MD·Randi 2☑otnik Shaul,,LLM,PhD·Lionel S.Zuckier,MD,MBA David J.Zorko,MD,MSc.Bram Rochwerg,MD,MScReceived:1 July 2022/Revised:13 December 2022/Accepted:19 December 2022The Author(s)2023Abstract This 2023 Clinical Practice Guideline providesCanadian Association of Emergency Physicians,the Nursethe biomedical definition of death based on permanentPractitioners Association of Canada,and the Canadiancessation of brain function that applies to all persons,asCardiovascular Critical Care Society.well as recommendations for death determination bycirculatory criteria for potential organ donors and deathKeywords brain death·circulatory death·death·determination by neurologic criteria for all mechanicallydeceased organ donation·definition of death·ventilated patients regardless of organ donation potential.neurologic deathThis Guideline is endorsed by the Canadian Critical CareSociety,the Canadian Medical Association,the CanadianAssociation of Critical Care Nurses,CanadianExecutive summaryAnesthesiologists'Society,the Canadian NeurologicalThis Clinical Practice Guideline was funded by HealthSciences Federation (representing the CanadianCanada and was developed as a partnership between theNeurological Society,Canadian Neurosurgical Society,Canadian Critical Care Society,Canadian Blood Services.Canadian Society of Clinical Neurophysiologists,Canadian Association of Child Neurology,Canadianand the Canadian Medical Association.The project'sSociety of Neuroradiology,and Canadian Strokeobjectives were to develop a unified brain-baseddefinition of death and update the criteria for itsConsortium),Canadian Blood Services,the Canadiandetermination after devastating bra
