Enfermedades Infecciosas y Microbiologia Clinica 41(2023)40-45Enfermedades Infecciosas yMicrobiologia ClinicaELSEVIERwww.elsevier.es/eimcConsensus documentExecutive summary of the consensus statement of the Spanish Societyof Infectious Diseases and Clinical Microbiology(SEIMC),SpanishSociety of Neurology(SEN),Spanish Society of Immunology(SEI),Spanish Society of Pediatric Infectology(SEIP),Spanish Society ofRheumatology(SER),and Spanish Academy of Dermatology andVenereology(AEDV),on the diagnosis,treatment and prevention ofLyme borreliosislose A.Oteo.,Hector Corominasb,Raquel Escudero,Fernando Farinas-GuerrerodJuan Carlos Garcia-Moncoe,Miguel A.Goenaga',Sara Guillen,Jose M.Mascar6,Aranzazu PortilloaCentre of Rickettsiosis and Arthropod-Borne Diseases(CRETAV)Department of Infectious Disecses,San Pedro University Hospital-Centre for Biomedical Research from La Rioja(CIBIR),Logrono,SpainSpanish Society of Rheumatology.Rheumatology and Systemic Autoimmune Diseases Department,Hospitalde la Santa Creui Sant PauHospital Dos de Maig.Barcelona,SpainSpecial Pathogens Reference and Research Laboratory,Centro Nacional de Microbiologia,Instituto de Salud Carlos Ill,Majadahonda,SpainSpanish Society of Immunology.nstitute ofincal mmunology and Infectious Diseases,YNMUN Biomedicine Group.Milag SpaineSpanish Society of Neurology.Department of Neurology.Hospital Universitario Basurto,Bilbao,SpainInfectious Diseases Service,Hospital Donostia,OSI Donostialdea.Instituto BioDonostin,San Sebastidn,SpainSpanish Society of Pediatric Infectology (SEIP).Department of Pediatrics HospitalUniversitario de Getafe,Madrid,SpainSpanish Academy of Dematology and Venereology,Department of Dermatology,Hospital Cinic de Barcelona,University of Barcelona,Barcelona,SpainABSTRACTKeywordsThe diagnosis of Lyme borreliosis (LB)is based on the epidemiological history,clinical manifestationsLyme borreliosisand microbiological findings in the early disseminated and late phases of the disease.Related to thisBorrelia burgdorferi sensu latoSpainfact,microbiological diagnostic techniques have recently appeared.Far from facilitating the diagnosisand the clinical-therapeutic management of LB patients,they are generating confusion.Herein,expertsGuidelinesConsensusand representatives of Spanish Scientific Societies [Spanish Society of Infectious Diseases and ClinicalMicrobiology(SEIMC).Spanish Society of Neurology(SEN).Spanish Society of Immunology(SEl).SpanishSociety of Pediatric Infectology(SEIP).Spanish Society of Rheumatology(SER),and Spanish Academy ofDermatology and Venereology (AEDV)]exposed the executive summary after reviewing the epidemiol-ogy,clinical spectrum,available diagnostic techniques for the diagnosis of Borrelia burgdorferi infection,therapeutic and prevention options of LB.By consensus,recommendations for microbiological diagnosisare offered together with those supporting the therapeutic management and prophylaxis of infection.2022 Sociedad Espanola deEnfermedades Infecciosas y M