CirculationAHA STATISTICAL UPDATEHeart Disease and Stroke Statistics-2022Update:A Report From the American HeartAssociationConnie W.Tsao,MD,MPH,FAHA,Chair;Aaron W.Aday,MD,MSc,FAHA;Zaid I.Almarzoog,MB,BCH;Alvaro Alonso,MD,PhD,FAHA;Andrea Z Beaton,MD,MS,FAHA;Marcio S.Bittencourt,MD,PhD,MPH,FAHA;Amelia K Boehme,PhD.MSPH:Alfred E.Buxton,MD:April P.Carson,PhD.MSPH,FAHA:Yonne Commodore-Mensah,PhD,MHS RN,FAHA;Mitchell S.V.Elkind,MD,MS FAHA;Kelly R.Evenson,PhD,MS,FAHA;Chete Eze-Nliam,MD,MPH;Jane F.Ferguson,PhD,FAHA;Giuliano Generoso,MD,PhD;Jennifer E.Ho,MD,FAHA;Rizwan Kalani,MD;Sadiya S.Khan,MD,MSc,FAHA;Brett M.Kissela,MD,MS,FAHA;Kristen L.Knutson,PhD;Deborah A.Levine,MD,MPH;Tene T.Lewis,PhD,FAHA;Junxiu Liu,PhD;Matthew Shane Loop,PhD,FAHA;Jun Ma,MD,PhD,FAHA;Michael E.Mussolino,PhD,FAHA;Sankar D.Navaneethan,MD,MS,MPH;Amanda Marma Perak,MD,MS,FAHA;Remy Poudel,MS,MPH,CPH;Mary Rezk-Hanna,PhD,FAHA;Gregory A.Roth,MD,MPH,FAHA;Emily B.Schroeder,MD,PhD,FAHA;Svati H.Shah,MD,MHS,FAHA;Evan L.Thacker,PhD;Lisa B.VanWagner,MD,MSc,FAHA;Salim S.Virani,MD,PhD,FAHA;Jenifer H.Voecks,PhD;Nae-Yuh Wang,PhD,MS FAHA;Kristine Yaffe,MD;Seth S.Martin,MD,MHS,FAHA,Vice Chair;on behalf of the American Heart Association Council onEpidemiology and Prevention Statistics Committee and Stroke Statistics SubcommitteeBackground:The American Heart Association,in conjunction with the National Institutes of Health,annually reports the mostDownloadedup-to-date statistics related to heart disease,stroke,and cardiovascular risk factors,including core health behaviors (smokingphysical activity,diet,and weight)and health factors (cholesterol,blood pressure,and glucose contro)that contribute tocardiovascular health.The Statistical Update presents the latest data on a range of major clinical heart and circulatory diseasefromconditions (including stroke,congenital heart disease,rhythm disorders,subclinical atherosclerosis,coronary heart diseaseheart failure,valvular disease,venous disease,and peripheral artery disease)and the associated outcomes (including qualityhttp:/of care,procedures,and economic costs)Methods:The American Heart Association,through its Statistics Committee,continuously monitors and evaluates sourcesof data on heart disease and stroke in the United States to provide the most current information available in the annualurnalsStatistical Update.The 2022 Statistical Update is the product of a full year's worth of effort by dedicated volunteer cliniciansand scientists,committed government professionals,and American Heart Association staff members.This year's editionincludes data on the monitoring and benefits of cardiovascular health in the population and an enhanced focus on socialdeterminants of health,adverse pregnancy outcomes,vascular contributions to brain health,and the global burden ofcardiovascular disease and healthy life expectancy.MarchResults:Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics.Conclusions