国际软组织肉瘤联合会(INSTRuCT)关于手术边缘定义统一的共识：手术边缘在儿童非横纹肌肉瘤软组织肉瘤中的意义

Received:1August 2022Revised:5 January 2023 Accepted:23 January 2023D0L10.1002/cam4.5671Cancer MedicineREVIEWWILEYThe significance of margins in pediatric Non-Rhabdomyosarcoma soft tissue sarcomas:Consensuson surgical margin definition harmonization fromthe INternational Soft Tissue SaRcoma ConsorTium(INSTRuCT)Monika Sparber-Sauer2 Andrea Ferrari Sheri L.Spunt Christian Vokuhl5Dana Casey Timothy B.Lautz?William H.Meyers David O.WalterhouseKristian W.Pajtler1011.12 Rita Alaggiol3 Andreas Schmidt14 Akmal Safwat15Beate Timmermann16 Patrizia Dall'Igna17 Sonja Chen's Aaron R.Weiss19Daniel Orbach20Klinikum der Landeshauptstadt Stuttgart gKAoR,Olgahospital,Stuttgart Cancer Center,Zentrum fur Kinder-,Jugend-und Prauenmedizin,Padiatrie 5(Padiatrische Onkologie,Hamatologie,Immunologie),Stuttgart,GermanyMedizinische Fakultit der Universitit Tubingen,Tubingen,GermanyPediatricOncology Unit,Fondazione IRCCS Istituto Nazionale Tumori,Milan,ItalyDepartment of Pediatrics,Stanford University School of Medicine,Palo Alto,California,United StatesSSection of PediatricPathology,University of Bonn,Bonn,GermanyDepartment of Radiation Oncology,University of North Carolina School of Medicine,Chapel Hill,North Carolina,United StatesDivision of PediatricSurgery,Department of Surgery,Northwestem University Feinberg School of Medicine,Chicago,Illinois,United StatesJimmy Everest Section of Pediatric Hematology Oncology,Department of Pediatrics,University of Oklahoma Health Sciences Center,OklahomaCity,Oklahoma,United StatesDivision of Pediatric Hematology/Oncology/Stem Cell Transplant,Department of Pediatrics,Ann&Robert H.Lurie Children's Hospital of Chicago,Northwestem University Feinberg School of Medicine,Chicago,Illinois,United StatesHopp-Children's Cancer Center,NCT Heidelberg(KiTZ),Heidelberg.GermanyDivision of PediatricNeurooncology,German Cancer Research Center(DKFZ),German Cancer Consortium(DKTK),Heidelberg,GermanyDepartment of Pediatric Hematology and Oncology,Heidelberg University Hospital,Heidelberg.GermanyPathology Unit,Department of Laboratories,Bambino Gesu Children's Hospital,IRCCS,Rome,ItalyDepartment of PediatricSurgery and Pediatric Urology,University Children's Hospital,Eberhard Karls University Tuebingen,Tuebingen,Germany5Oncology Department and Danish Center for Particle Therapy,Aarhus University Hospital,Aarhus,DenmarkDepartment of Particle Therapy,University Hospital Essen,West German Proton Therapy Centre Essen(WPE),West German Cancer Center(WTZ☑，German Cancer Consortium(①KTK),GermanyPediatricSurgery,Department of Emergencies and Organ Transplantation,University of Bari,Bari,ItalyDepartment of Pathology and Laboratory Medicine,Nationwide Children's Hospital,Columbus,Ohio,United StatesDepartment of Pediatrics,Maine Medical Center,Portland,Maine,United StatesSIREDO Oncology Center(Care,Innovation and Research for Children,Adolescents and Young Adults with Cancer),PSLUniversity,Institut Curie,Paris,FranceThis isan open access article under the terms of th