商Check for updatesReceived:7 June 2022 Revised:11 July 2022Accepted:26 July 2022D0L10.1002/cncr.34479ORIGINAL ARTICLEAnnual report to the nation on the status of cancer,part 1:National cancer statisticsKathleen A.Cronin PhD,MPH1 Susan Scott MPH1 Albert U.Firth BS2Hyuna Sung PhD3 S.Jane Henley MSPH4Recinda L.Sherman MPH,PhD,CTR5 Rebecca L.Siegel MPH3Robert N.Anderson PhD6 Betsy A.Kohler MPH5 Vicki B.Benard PhD4Serban Negoita MD,DrPH1 Charles Wiggins PhD?William G.Cance MD3Ahmedin Jemal DVM,PhD3Division of Cancer Control and PopulationSciences,National Cancer Institute,Bethesda.AbstractMaryland,USABackground:The American Cancer Society,the Centers for Disease Control and2Information Management Services,IncRockville,Maryland.USAPrevention,the National Cancer Institute,and the North American Association of3Department of Surveillance and Health EquityCentral Cancer Registries collaborate to provide annual updates on cancer occur-Science,American Cancer Society.Atlanta,rence and trends in the United States.Georgia,USAMethods:Data on new cancer diagnoses during 2001-2018 were obtained fromDivision of Cancer Prevention and Control.National Center for Chronic Diseasethe North American Association of Central Cancer Registries'Cancer in NorthPrevention and Health Promotion.Centers forAmerica Incidence file,which is comprised of data from Centers for DiseaseDisease Control and Prevention,Atlanta,Georgia,USAControl and Prevention-funded and National Cancer Institute-funded,population-SNorth American Association of Centralbased cancer registry programs.Data on cancer deaths during 2001-2019 wereCancer Registries,Springfeld,lllinois,USAobtained from the National Center for Health Statistics'National Vital StatisticsNational Center for Health Statistics,CentersSystem.Five-year average incidence and death rates along with trends for allfor Disease Control and PreventionHyattsville,Maryland,USAcancers combined and for the leading cancer types are reported by sex,racial/7New Mexico Tumor Registry.University ofethnic group,and age.New Mexico Comprehensive Cancer Center,Albuquerque,New Mexico.USAResults:Overall cancer incidence rates were 497 per 100,000 among malesBAmerican Cancer Society,Atlanta.Georgia,(ranging from 306 among Asian/Pacific Islander males to 544 among BlackUSAmales)and 431 per 100,000 among females (ranging from 309 among Asian/Pacific Islander females to 473 among American Indian/Alaska Native females)CorrespondenceKathleen A.Cronin,Division of Cancerduring 2014-2018.The trend during the corresponding period was stableControl and Population Sciences,Nationalamong males and increased 0.2%on average per year among females,withCancer Institute,9609 Medical Center Drive.Room 4E454.Bethesda,MD 20892-9765.differing trends by sex,racial/ethnic group,and cancer type.Among males,USA.incidence rates increased for three cancers (including pancreas and kidney),Email:cronink@mail.nih.govwere stable for seven cancers (including prostate),and decreased for eight