Rheumatology Advances in Practice,2023,7(2),rkad039https://doi.org/10.1093/rap/rkad039GuidelineBritish Society forRHEUMATOLOGYRheumatologyADVANCES IN PRACTICEOXFORDGuidelineTreatment of axial spondyloarthritis with biologic andtargeted synthetic DMARDs:British Society forRheumatology guideline scopeSizheng Steven Zhao1.*,Stephanie R.Harrison23,Antoni Chan4,Nick Clarke5,Charlotte Davis,Joe Eddison5,William J.Gregory Gareth T.Jones Helena Marzo-Ortega2.3,Daniel J.Murphy10,Virinderjit Sandhu11,Raj Sengupta12,Stefan Siebert13,Ben Thompson14,Dale Webb15,Max Yates16.17,Karl Gaffney17dedCentre for Epidemiology Versus Arthritis,Division of Musculoskeletal and Dermatological Science,School of Biological Sciences,Facultyof Biological Medicine and Health,The University of Manchester,Manchester Academic Health Science Centre,Manchester,UKLeeds Institute of Rheumatic and Musculoskeletal Medicine,University of Leeds,Leeds,UKNIHR Leeds Biomedical Research Centre,Leeds Teaching Hospitals Trust,Leeds,UKDepartment of Rheumatology,Royal Berkshire NHS Foundation Trust,Reading,UKPPatient ExpertDepartment of Rheumatology,Leeds Teaching Hospitals Trust,UKRheumatology Department,Salford Royal Hospital,Northern Care Alliance NHS Foundation Trust,Greater Manchester,UKFaculty of Health and Education,Manchester Metropolitan University,Manchester,UK8Aberdeen Centre for Arthritis and Musculoskeletal Health(Epidemiology Group),University of Aberdeen,Aberdeen,UK0Department of Rheumatology,Honiton Surgery,Royal Devon Exeter Hospital,Exeter,UKDepartment of Rheumatology,St George's University Hospitals NHS Foundation Trust,London,UK2Royal National Hospital for Rheumatic Diseases,Royal United Hospitals,Bath,UK3School of Infection and Immunity,University of Glasgow,Glasgow,UKRheumatology Department The Newcastle-upon-Tyne Hospitals NHS Foundation Trust Newcastle-upon-Tyne,UK5National Axial Spondyloarthritis Society (NASS),London,UKCentre for Epidemiology,Norwich Medical School,University of East Anglia,Norwich,UKRheumatology Department,Norfolk Norwich University Hospitals NHS Foundation Trust,Norwich,UKNICE accreditedwww.nice.org.uk/accreditationuestNICE has accredited the process used by BSR to create its clinical guidelines.The tem began on 27 February 2012 and the current renewed accreditation isvalid until31 December 2023.More information on accreditation can be viewed at www.nice.org.uk/accreditation.*Correspondence to:Sizheng Steven Zhao,Centre for Epidemiology Versus Arthritis,Division of Musculoskeletal and Dematological Science,School ofBiological Sciences,Faculty of Biological Medicine and Health,The University of Manchester,Manchester Academic Health Science Centre,Oxford Road,Manchester M13 9LJ,UK.E-mail:sizheng.zhao@manchester.ac.ukAbstractPhamacological management has advanced considerably since the 2015 British Society for Rheumatology axial spondyloarthritis (axSpA)guide-line to incorporate new classes of biologic DMARDs (bDMARDs,including biosimilars),targeted synth
