Infection Control Hospital Epidemiology (2023),1-22dot10.1017/ice.2022.304SHEASHEA Expert GuidanceSHEA/IDSA/APIC Practice Recommendation:Strategies to preventhealthcare-associated infections through hand hygiene:2022 UpdateJanet B.Glowicz PhD,RN,CIC,Emily Landon MD2,Emily E.Sickbert-Bennett PhD,MS,CIC34,Allison E.Aiello PhD5,Karen deKay MSN,RN,CNOR,CIC5,Karen K.Hoffmann BSN,MS,CIC7,Lisa Maragakis MD,MPHB,Russell N.Olmsted MPH,CIC,Philip M.Polgreen MD,MPH10 Polly A.Trexler MS,CIC11,Margaret A.VanAmringe MHS12,Amber R.Wood MSN,RN,CNOR,CIC5,Deborah Yokoe MD,MPH13 andKatherine D.Ellingson PhD14Division of Healthcare Quality and Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia,2Department of Infectious Diseases,MacLeanCenter for Clinical Medical Ethics,The University of Chicago Medical Center,Chicago,Illinois,Department of Infectious Diseases and Department ofEpidemiology,University of North Carolina Chapel Hill,North Carolina,Carolina Antimicrobial Stewardship Program,UNC Gillings School of Global PublicHealth,UNC Hospitals,Chapel Hill,North Carolina,Department of Epidemiology,Robert N.Butler Columbia Aging Center,Columbia University,New York,New York,Association of periOperative Registered Nurses(AORN),Denver,Colorado,'Division of Infectious Diseases,University of North Carolina School ofMedicine,Chapel Hill,North Carolina,Department of Medicine,Johns Hopkins University School of Medicine,The Johns Hopkins Hospital,Baltimore,Maryland,Trinity Health,Livonia,Michigan,Department of Internal Medicine,Carver College of Medicine,University of lowa,lowa City,lowa,Healthcare Epidemiologyand Infection Control,The Johns Hopkins Health System,Baltimore,Maryland,The Joint Commission,Office of Public Policy and Government Relations,Washington,DC,Department of Medicine,University of Califomia San Francisco,UCSF Health-UCSF Medical Center,San Francisco,Califomia andMDepartment of Epidemiology and Biostatistics,College of Public Health,The University of Arizona,Tucson,ArizonaAbstractThe purpose ofthis document is to highlight practical recommendations to assist acute-care hospitals in prioritization and implementation ofstrategies to prevent healthcare-associated infections through hand hygiene.This document updates the Strategies to Prevent Healthcare-Associated Infections in Acute Care Hospitals through Hand Hygiene,published in 2014.This expert guidance document is sponsored bythe Society for Healthcare Epidemiology (SHEA).It is the product of a collaborative effort led by SHEA,the Infectious Diseases Societyof America,the Association for Professionals in Infection Control and Epidemiology,the American Hospital Association,and The JointCommission,with major contributions from representatives of a number of organizations and societies with content expertise.(Received 14 November 2022;accepted 15 November 2022)PurposeEpidemiology (APIC),the American Hospital AssociationPreviously published guidelines provided comprehensive recom-(AHA),and The J