European Heart Journal Supplements (2023)25(Supplement D),D299-D309The Heart of the Mat terhttps://doi.org/10.1093/eurheartjsupp/suad100ESCEuropean Societyof CardiologyANMCO position paper on the management ofhypercholesterolaemia in patients with acutecoronary syndromeLeonardo De Luca 1*,Carmine Riccio2,Alessandro Navazio3,Serafina Valente,Manlio Cipriani5,Marco Cordas,Alfredo De Nardo7Giuseppina Maura Francese8,Cosimo Napoletano9,Emanuele Tizzani10Loris Roncon11,Pasquale Caldarola12,Michele Massimo Gulizia,Domenico Gabrielli1,Fabrizio Oliva13,and Furio Colivicchi14Dipartimento di Scienze Cardio-Toraco-Vascolari,UOC Cardiologia,AO San Camillo-Forlanini,Circonvallazione Gianicolense,87,00152 Roma,Italy:-UOSD Follow-up del Paziente Post-Acuto,Dipart imento Cardio-Vascolare,AORN Sant 'Anna e SanSebastiano,Caserta 81100,Italy;3SOC Cardiologia Ospedaliera,Presidio OspedalieroArcispedale SantaMaria Nuova,AziendaUSL di Reggio Emilia-IRCCS,Reggio Emilia 42121,Italy;Dipartimento Cardio-Toracico,AOU Senese,Ospedale Santa Mariaalle Scotte,Siena 53100,Italy;5UOC Cardiologia,ISMETT(Istituto Mediterraneo per i Trapianti e Terapie ad altapecializzazione),Palermo 90121,Italy;S.C.Cardiologia,Azienda Ospedaliera G.Brotzu,Cagliari09121,Italy;UOCardiologia-UTIC,Ospedale Civile 'G.Jazzolino',Vibo Valentia 89900,Italy;UOC Cardiologia,Ospedale Garibaldi-Nesima,Azienda di Rilievo Nazionale e Alta Specializzazione'Garibaldi',Catania 95100,Italy;UOC Cardiologia-UTIC-Emodinamica,Presidio Ospedaliero 'G.Mazzini',Teramo 64100,Italy;10Dipartimento di Cardiologia,Ospedale degli Infermi,Rivoli (TO),Torino 10098,Italy;UOC Cardiologia,Ospedale Santa Maria della Misericordia,Rovigo 45100,Italy;1UOC Cardiologia-UTIC,AO Ospedale San Paolo,Bari 70100,Italy;Unita di Cure Intensive Cardiologiche,Cardiologia 1-Emodinamica,DipartimentoCardiotoracovascolare 'A.De Gasperis',ASST Grande Ospedale Metropolitano Niguarda,Milano 20162,Italy;and 14UOCCardiologia Clinica e Riabilitativa,Presidio Ospedaliero San Filippo Neri-ASL Roma 1,Roma 00176,ItaliaKEYWORDSPatients suffering from acute coronary syndrome (ACS)present a high risk of recur-Hypercholesterolaemia;rence and new adverse cardiovascular events after hospital discharge.Elevated plas-Acute coronary syndrome;ma LDL-cholesterol (LDL-C)levels have been shown to be a causal factor for theFast-track;development of coronary heart disease,and robust clinical evidence has documentedVery high risk;that LDL-C levels decrease linearly correlates with a reduction in cardiovascularStatins;events.Recent studies have also demonstrated the safety and efficacy of an earlyEzetimibe;and significant reduction in LDL-C levels in patients with ACS.In this position paper,Bempedoic acid;Italian Association of Hospital Cardiologists proposes a decision algorithm on earlyPCSK9 inhibitorsadoption of lipid-lowering strategies at hospital discharge and short-term follow-upof patients with ACS,in the light of the multiple evidence generated in recent yearson the tre
