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價Check for updatesBAP GuidelinesEvidence-based consensus guidelines for thePsychopharmmanagement of catatonia:Recommendationsfrom the British Association forJoumal of Psychopharmacology1-43PsychopharmacologyThe Author(s)2023©0Article reuse guidelines:sagepub.com/journals-permissionsD0I:10.1177/02698811231158232Jonathan P Rogers1.2,Mark A Oldham3,Gregory Fricchione4.5,journals.sagepub.com/home/jopGeorg Northoff,Jo Ellen Wilson,Stephan C Mann,Andrew Francis0SAGEAngelika Wieck11.12,Lee Elizabeth Wachtel13.14,Glyn Lewis1Sandeep Grover15,Dusan Hirjak16,Niraj Ahuja17,Michael S Zandi18,19,Allan H Young20.2,Kevin Fone21,Simon Andrews22,David Kessler23,Tabish Saifee19,Siobhan Gee24.25,David S Baldwin26and Anthony S David27AbstractThe British Association for Psychopharmacology developed an evidence-based consensus guideline on the management of catatonia.A group ofinternational experts from a wide range of disciplines was assembled.Evidence was gathered from existing systematic reviews and the primary literature.Recommendations were made on the basis of this evidence and were graded in terms of their strength.The guideline initially covers the diagnosis,aetiology,clinical features and descriptive epidemiology of catatonia.Clinical assessments,including history,physical examination and investigations arethen considered.Treatme nt with benzodiazepines,electroconvulsive the rapy and other pharmacological and neuromodulatory therapies is covered.Specialregard is given to periodic catatonia,malignant catatonia,neuroleptic malignant syndrome and antipsychotic-induced catatonia.There is attention to theneeds of particular groups,name ly children and adolescents,older adults,women in the perinatal period,people with autism spectrum disorder and thosewith certain medical conditions.Clinical trials were uncommon,and the recommendations in this guideline are mainly informed by small observationalstudies,case series and case reports,which highlights the need for randomised controlled trials and prospective cohort studies in this area.KeywordsCatatonia,catatonic schizophrenia,guideline,treatment,benzodiazepine,electrocorvulsive therapy,neuroleptic malignant syndromeDivision of Psychiatry.University College London,London,UK*Department of Psychiatry and Psychotherapy,Central Institute of2South London and Maudsley NHS Foundation Trust,London,UKMental Health,Medical Faculty Mannheim,University of Heidelberg.Department of Psychiatry,University of Rochester Medical Center,Mannheim,GermanyRochester,NY,USARegional Affective Disorders Service,Cumbria,Northumberland,Tyne"Department of Psychiatry,Massachusetts General Hospital,Boston,and Wear NHS Foundation Trust,Newcastle,UKMA,USAQueen Square Institute of Neurology,University College London,SHarvard Medical School,Boston,MA,USALondon,UKMind,Brain Imaging and Neuroethics Research Unit,The Royal'sNational Hospital for Neurology and Neurosurgery,London,UKInstitute of Mental Health Research,University of Ottawa,Ottawa,2Department of