真Check for updatesReceived:28 February 2023 Accepted:31 March 2023D0:10.1111/jpe.13823Joumal of ClinicalCLINICAL PRACTICE GUIDELINEPeriodontologyWILEYPrevention and treatment of peri-implant diseases-The EFPS3 level clinical practice guidelineDavid Herrera1 Tord Berglundh2 Frank Schwarz3 lain Chapple45Soren Jepsen Anton Sculean7 Moritz Kebschull 4.5.8Panos N.Papapanou3 Maurizio S.Tonetti Mariano Sanz1 on behalf of theEFP workshop participants and methodological consultantETEP(Etiology and Therapy of Periodontal and Peri-implant Diseases)Research Group,University Complutense of Madrid,Madrid,Spain2Department of Periodontology,Institute of Odontology.The Sahlgrenska Academy.University of Gothenburg.Gothenburg.SwedenDepartment of Oral Surgery and Implantology.ohann Wolfgang Goethe-University.Frankfurt,GemmanyPeriodontal Research Group,Institute of Clinical Sciences,College of Medical Dental Sciences,The University of Birmingham,Birmingham,UKSBirmingham Community Healthcare NHS Foundation Trust.Birmingham,UKDepartment of Periodontology.Operative and Preventive Dentistry.University Hospital Bonn.Bonn.Germany7Department of Periodontology.School of Dental Medicine,University of Bem.Bern,SwitzerlandDivision of Periodontics,Section of Oral,Diagnostic and Rehabilitation Sciences,College of Dental Medicine,Columbia University.New York,New York,USAShanghai Periolmplant Innovation Center.Department of Oral and Maxillo-facial Implantology.Shanghai Key Laboratory of Stomatology.National Clinical ResearchCentre for Oral Diseases,Shanghai Ninth People Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,ChinaCorrespondenceDavid Herrera,ETEP (Etiology and Therapy ofAbstractPeriodontal and Peri-implant Diseases)Background:The recently published Clinical Practice Guidelines(CPGs)for the treat-Research Group.Faculty of Odontology.University Complutense of Madrid,Plazament of stages I-IV periodontitis provided evidence-based recommendations forRamon y Cajal s/n (Ciudad Universitaria).28040 Madrid,Spain.treating periodontitis patients,defined according to the 2018 classification.Peri-Email:davidher@ucm.esimplant diseases were also re-defined in the 2018 classification.It is well establishedFunding infommationthat both peri-implant mucositis and peri-implantitis are highly prevalent.In addition,European Federation of Periodontologyperi-implantitis is particularly challenging to manage and is accompanied by signifi-cant morbidity.Aim:To develop an $3 level CPG for the prevention and treatment of peri-implantdiseases,focusing on the implementation of interdisciplinary approaches required toprevent the development of peri-implant diseases or their recurrence,and to treat/rehabilitate patients with dental implants following the development of peri-implantdiseases.Materials and Methods:This S3 level CPG was developed by the European Federa-tion of Periodontology,following methodological guidance from the Association ofScientific Medical Societies in Germany and