育Check for updatesESCEuropean Journal of Heart Failure 2023)25,457-468POSITION PAPEREuropean Societydot10.1002/ehf.2814of CardiologyInotropic therapy in patients with advancedheart failure.A clinical consensus statementfrom the Heart Failure Association of theEuropean Society of CardiologyFinn Gustafsson1*,Kevin Damman2,Sanem Nalbantgil3,Linda W.Van Laake4,Laurens F.Tops5,Thomas Thum6,Stamatis Adamopoulos7,Michael Bonios7,Andrew JS Coats,Maria G.Crespo-Leiro%,Mandeep R.Mehra10,Gerasimos Filippatos11,Loreena Hill12,Marco Metra13,Ewa Jankowska14,Nicolaas de Jonge4,David Kaye15,Marco Masetti16,John Parissis17,Davor Milicic18,Petar Seferovic19,Giuseppe Rosano20,and Tuvia Ben Gal21Department of Cardiology.Rigshospitalet.University of Copenhagen,Kobenhavn,Denmark2University of Groningen,Depar tment of Cardiology.University Medical CenterGroningen,Groningen,The Netherlands:3Cardiology Department.Faculty of Medicine,Ege University.Izmir.Turkey:Department of Cardiology.University Medical CenterUtrecht,Utrecht.The Netherlands 5Department of Cardiology.Leiden University Medical Center,Leiden,The Netherlands:5Institute of Molecular and Therapeutic Strategies(IMTTS).Hamover Medical School,and Fraunhofer Institute of Taxicology and Experimental Medicine.Hannover.Germany:7Onassis Cardiac Surgery Center.Athens.Greece:University of Warwick.Coventry.UK:Servico de Cardiologa.Complejo Hospitalario Universitario deA Corufa(CHUAC).CIBERCV.Instituto de Investigacion Biomedica deA Corufa(INIBIC).A Corufa,Spain:10Center for Advanced Heart Disease,Brigham and Women's Hospital and Harvard Medical School,Boston,MA,USA:11Heart FailureUnit Department of Cardiology.Athens University Hospital Attikon National and Kapodistrian University of Athens.Schoolof Medicine.Athens.Greece:12School of Nursing&Midwifery,Queen's University,Belfast,UK:13Cardiology.ASST Spedali Civili and University of Brescia,Brescia,Italy:1Institute of Heart Diseases,Wroclw Medical Universityand Institute of Heart Diseases,University Hospital,Wroclw,Polnd:15The Alfred Hospital,Melbourne,Vic,Australia:Baker Heart and Diabetes Institute,Melbourne,Australia16Heart Failure and Transplant Unit.IRCCS Azienda Ospedaliero-Universitariadi Bologna.Bologna.ltaly 17 Heart Failure Unit and University Clinic of Emergency Medicine.Attikon University Hospital,National and Kapodistrian University of Athens Medical School,Athens.Greece:1 Department of Cardiovascular Diseases.University of ZagrebSchool of Medicine University Hospital Centre Zagreb,Zagreb.Croatia:1Faculty of Medicine.University of Begrade,and Serbian Academy of Arts and Sciences.Belgrade.Serbia:20St George's University Medical School of London,London,UK:and 21 Heart Failure Unit,Cardiology Depar tment.Rabin Medical Center.Sacker Faculty of Medicine,TelAviv University.Tel Aviv,IsraelRecelved 27 October 2022;revsed 20 February 2023:accepted 24 February 2023:online publish-aheadof-print 10 March 2023This clinical consensus statement reviews the use of inotropic su