2023ILEP意见书：贝培多酸(Bempedoicacid)用于血脂异常和心血管风险的管理

ARTICLE IN PRESSYPCAD-01364:No of Pages 10Progress in Cardiovascular Diseases xxx(2023)xxxContents lists available at ScienceDirectProgress in Cardiovascular DiseasesELSEVIERjournal homepage:www.onlinepcd.comBempedoic acid in the management of lipid disorders and cardiovascularrisk.2023 position paper of the International Lipid Expert Panel (ILEP)Maciej Banach Peter E.PensonMichel FarnierZlatko Fras Gustavs Latkovskisi Ulrich LaufsFrancesco Paneni m.n,Paolo PariniP,Matteo Pirro 9,Zeliko Reiner,Michal Vrablik s,Carlos EscobartDepartment of Preventive Cardiology and Lipidolgy.Medical University ofLodz(MUL).Lodz,PolandDepartme ofCardiology and Congenital Diseases of Adults,Palish Mothers Memori Hospital Research Institte(PMMHRI)Lodz PolandCardiovasatlar Research Centre,University ofZie lona Gora Zie lona Gora PolandCiccarone Centerorthe Prevention of Cardiovscular Disese Johns Hopkins University School of Medicine,Baltimare,MD.USAClinical Phamagy Therapeutics Research Group School ofPhammacy Biomolecular Sciences,Liverpool John Moores University.Liverpool UKLiverpool Centre for Cardiovascular Science,Liverpool UKPhysiopathology and Epidemiology Cerebro-Cardiovascular (PEC2),University of Burgundy and Franche Comte,Dijon,FranceDepartment of Vascular Disease,University Medical Center Ljubljana,Ljubljana,Slovenia"Facuty ofMedic ine,University of Ljubljana,Ljubljana,SloveniaInstitute of Cardiology and Regenerative Medicine,University of Latvia Riga Latvia*Latvian Centerof Cardiology,Pals Stradins Clinical University Hospiml Riga LatviaKlinik und Pohklinik fur Kardiologie.UniversitatsklinikumLeipzig.Leipzig GermanyUniversity Heart Center,Department of Cardiology.University Hospital Zrich,Zurich,Switzerland"Center for Translationaland Experimental Cardiology(CTEC).University HospitalZurich and University of Zurich,Zurich SwitzerlandCardoMetabolicUnit Department of Medicine d Deparment ofry Medicine,Krinska nstinte Stockhom SwedenMedical Unit Endocrinology.Theme Inflammation and Ageing.Karolinska University Hospital,Stockholm,SwedenUnit of Irtemal Medicine,Angiology and Arteriosderosis Diseases Department of Medicine,University of Pengia,Pengin,ImlyDepartment of Intemal Diseases,University Haspital Center Zagreb,Zagreb,Croatia3rd Department of Medicine-Department of Endocrinology and Metabolism,Charies University.Prague,Czech RepublicCardiology Departmert,University Hospital La Paz,Madrid,SpainARTICLE INFOABSTRACTAvailable online xxoxxCardiovascular disease (CVD)is a chronic non-communicable disease(NCD)and the predominant cause of mor-Keywords:bidity and mortality worldwide.Substantial reductions in the CVD prevalence have been achieved in recent yearsBempedoic acidby the attenuation of risk factors(particularly hypertension and dyslipidaemias)in primary and secondary pre-ETC1002vention.Despite the remarkable success of lipid lowering treatments,and of statins in particular,in reducing theAtherosclerotic cardiovascular diseaserisk of CVD.there is still an