The Journal ofHeart and LungTransplantationELSEVIERhttp://www.jhltonline.orgThe International Society for Heart and LungCrossMarkTransplantation (ISHLT)guidelines for the care ofheart transplant recipientsAngela Velleca,MHDS,RN,3.1 Michael A Shullo,PharmD,51Kumud Dhital,BMBCh,PhD,Estela Azeka,MD,d Monica Colvin,MD,eEugene DePasquale,MD,Marta Farrero,MD,PhD,9 Luis Garcia-Guereta,MD,hGina Jamero,NP,Kiran Khush,MD,'Jacob Lavee,MD,Stephanie Pouch,MD,Jignesh Patel,MD,PhD,a CJ Michaud,PharmD,Michael A Shullo,PharmD,Stephan Schubert,MD,Annalisa Angelini,MD,Lilibeth Carlos,MPharm,Sonia Mirabet,MD,P Jignesh Patel,MD,PhD,Michael Pham,MD,9 Simon Urschel,MD,"Kyung-Hee Kim,MD,sShelly Miyamoto,MD,t Sharon Chih,MD,Kevin Daly,MD,Paolo Grossi,MD,wDouglas L Jennings,PharmD,x In-cheol Kim,MD,2 Hoong Sern Lim,MD,aaEndorsed by the Pediatric Heart Transplant Society.HLA,human leukocyte antigen:HPLC,high-performance liquid chromatog-Independent Expert Reviewers:David Baran,Tiffany Buda,Adamraphy:HPV,human papillomavirus;HRS,Heart Rhythm Society;HSV,her-Cochrane,Maria Crespo Leiro,Anne Dipchand,Brian Feingold,Kathleenpes simplex virus;HT,heart transplant;ICU,intensive care unit;IgGrady.Edward Horn,Maryl Johnson,Donna Mancini,Sean Pinney,immunoglobulin;IgG,immunoglobulin G:IH,Isohemagglutinin;INR,inter-Heather Ross,Kari Wujcik,Andreas Zuckermann.Abbreviations:AAIR.national nommalized unit;IABP,intra-aortic balloon pump;ISHLT,Intema-atrium paced,atrium sensed inhibited rate modulation:ABOi,ABO incom-tional Society for Heart and Lung Transplantation;IUD,intrauterine device;patible:ACC.American College of Cardiology:ACEI,angiotensin convert-IV.intravenous:IVUS.intravascular ultrasound:LV.left ventricle:LVAD.ing enzyme inhibitor:ACR,acute cellular rejection;ACT,activated clottingleft ventricular assist device;LVEF,left ventricular ejection fraction:LVH.time:ADA,American Diabetes Association:AHA,American Heart Associa-left ventricular hypertrophy;MAOL,monoamine oxidase inhibitors;MCStion:AMR,antibody-mediated rejection:AP,aerosolized pentamidine:mechanical circulatory support;MDRD quation,modified diet in renal dis-aPTT,activated partial thromboplastin time;ARB.angiotensin receptorease equation;MFI,mean fluorescent intensity;MMF,mycophenolate mofe-blocker;ASD,atrial septal defect;ATG,anti-thymocyte globulin;AV,arte-til:MPA,mycophenolic acid:mTOR,mammalian target of rapamycin;riovenous;AZA,azathioprine;BiV,biventricular;BMD,bone mass density;MVO2,mixed venous oxygen;PAWP,pulmonary artery wedge pressure;BNP,brain natriuretic peptide:BPAR,proven acute rejection;CAV,cardiacPCC,prothrombin plasma concentrates;PFA-100,platelets function assayallograft vasculopathy:CBCR,center-based cardiac rehabilitation;CCB,cal-100;PGF,primary graft failure:PRA.panel reactive antibodies;PRES.poscium channel blocker,CCTA,Coronary computed tomography angiography:terior reversible leukoencephalopathy:PCSK9,Proprotein convertase subtili-CEDIA,cloned enzyme donor immunoassay method:CHD,congenital heart