Original ArticleAnnals of Dermatology 2023;35(3):205-216 https://doi.ong/10.5021/ad.22.167周Check for updatesGuidelines for the Management of Patients with AlopeciaAreata in Korea:Part lI Systemic TreatmentHyunsun Park,Jung Eun Kim',Jee Woong Choi,Do Young Kim,Yong Hyun Jang',Young Lee',Jiehyun Jeon,Hyun-Tae Shin',Min Sung Kim,Jung Won Shin,Sung Bin Cho,Bark-Lynn Lew",Gwang Seong Choi'Department of Dermatology,SMG-SNU Boramae Medical Center,Seoul,Korea;'Department of Dermatology,College of Medicine,The Catholic University of Korea,Seoul,Korea;'Department of Dermatology,Ajou University School of Medicine,Suwon,Korea;Department of Dermatology,Yonsei University College of Medicine,Seoul,Korea;Department of Dermatology,School of Medicine,Kyungpook National University,Daegu,Korea;'Department of Dermatology,School of Medicine,Chungnam National University,Daejeon,Korea;Department of Dermatology,Guro Hospital,Korea University College of Medicine,Seoul,Korea;Department of Dermatology,InhaUniversity School of Medicine,Incheon,Korea;Department of Dermatology,School of Medicine,Chosun University,Gwangju,Korea;Department of Dermatology,Seoul National University Bundang Hospital,Bundang,Korea;Yonsei Seran Dermatology and Laser Clinic,Seoul,Korea;"Department of Dermatology,Kyung Hee University School of Medicne,Seoul,KoreaReceived September 13,2022Background:Alopecia areata (AA)is a chronic disease with an unpredictable course andRevised December 17,2022can have a severe psychological impact on an individual.Accepted January 24,2023Objective:To provide evidence and consensus-based statements regarding the treatment ofpatients with AA in Korea.Methods:We searched for relevant studies from inception to May 2021 regarding the sys-temic treatment of AA.Evidence-based recommendations were also prepared.The evidencefor each statement was graded and classified according to the strength of the recommenda-tions.Hair experts from the Korean Hair Research Society(KHRS)voted on the statement,and an agreement of75%or greater was considered as having reached consensus.Results:Current evidence supports the efficacy of systemic corticosteroids,oral cyclospo-rine monotherapy or combination with systemic corticosteroids,and oral Janus kinaseCorresponding Authorinhibitors in severe AA patients.Systemic steroids may be considered for pediatric patientsBark-Lynn Lewwith severe AA.A consensus was achieved in three out of nine (33.3%),and one out of threeDepartment of Dermatology,Kyung HeeUniversity Hospital at Gangdong,892(33.3%)statements pertaining to systemic treatment in adult and pediatricAA,respectively.Dongnam-ro,Gangdong-gu,Seoul 05278,Conclusion:The present study produced up-to-date,evidence-based treatment guidelinesKoreafor AA associated with the consensus obtained by experts based on the Korean healthcareTel:+82-2-440-7329system.Fax:+82-2-440-7336E-mail:bellotte@hanmail.nethttps:/orcid.org0000-00034443-4161Keywords:Alopecia areata,Guideline,Korea,Systemic,Therapeutics,Tre
