Clinical Review EducationJAMA I US Preventive Services Task Force RECOMMENDATION STATEMENTScreening for Depression and Suicide Risk in AdultsUS Preventive Services Task Force Recommendation StatementUS Preventive Services Task ForceEditorial page2026IMPORTANCE Major depressive disorder (MDD),a common mental disorder in the US,may⊕Multimediahave substantial impact on the lives of affected individuals.If left untreated,MDD caninterfere withdaily functioning and can also be associated withan increased risk ofRelated article page2068 andcardiovascular events,exacerbation of comorbid conditions,or increased mortality.JAMA Patient Page page2102OBJECTIVE The US Preventive Services Task Force(USPSTF)commissioned a systematicSupplemental contentreview to evaluate benefits and harms of screening.accuracy of screening.and benefits andCME at jamacmelookup.comharms of treatment of MDD andsuicide risk in asymptomatic adults that would be applicableRelated article atto primary care settings.jamanetworkopen.comPOPULATION Asymptomatic adults 19 years or older,including pregnant and postpartumpersons.Older adults are defined as those 65 years or older.EVIDENCE ASSESSMENT The USPSTF concludes with moderate certainty that screening forMDD in adults,including pregnant and postpartum persons and older adults,has a moderatenet benefit.The USPSTF concludes that the evidence is insufficient on the benefit and harmsof screening for suicide risk in adults,including pregnant and postpartum persons and olderadults.RECOMMENDATION The USPSTF recommends screening for depression in the adultAuthor/GroupInformation:The USpopulation,including pregnant and postpartum persons and older adults.(BPreventive Services Task Forcerecommendat ion)The USPSTF concludes that the current evidence is insufficient to assess(USPSTF)members are listed at thethe balance of benefits and harms of screening for suicide risk in the adult population,end of this article.including pregnant and postpartum persons and older adults.(I statement)Corresponding Author:Michael J.Barry.MD,Informed MedicalDecisions Program,Massachusetts4MA.202332923)2057-2067.dot10.100/jama.2023.9297General Hospital,50 Staniford St,Boston,MA 02114 (chair@uspstf.net)Summary of RecommendationsPopulationRecommendationGradeAdults,including pregnant andThe USPSTF recommends screening for depression in thepostpartum persons,and olderadult po pulation,including pregnant and postpartum persons,Badults(65 years orolder)as well as older adults.Adults,including pregnant andThe USPSTF concludes that the current evidence is insufficientpostpartum persons,and olderto assess the balance of benefits and harms of screening foradu lts(65 years or older)suicide risk in the adult population,including pregnant andpostpartum persons,as wellas older adults.USPSTF indicatesUS PreventiveServices Task Force.See the Summary of Recommendations figure.It bases its recommendations on the evidence of both the ben-Preambleefits and harms of the service and an as