中国介入心脏病学杂志2023年4月第31卷第4期Chin J Intervent Cardiol,Apl2023,ol31,No.4241·专家共识冠状动脉CT血流储备分数应用临床路径中国专家共识中国医师协会心血管内科医师分会超声心动图和影像学组《中国介入心脏病学杂志》编辑委员会【摘要】目前血流储备分数(FFR)被认为是心外膜冠状动脉狭窄功能性评价的“金标准”，但由于各种原因在实际临床中FFR的应用受到一定限制。基于冠状动脉CT血管造影(CCTA)影像数据应用高级计算流体力学及深度学习等方法获得的冠状动脉CT血流储备分数(CT-FFR)能同时提供冠状动脉的解剖和生理学信息，成为临床研究和应用的新热点。CT-FFR在国内临床实践中的使用仍处于探索阶段。本专家共识介绍了CT下FFR的基本原理及诊断效能、工作流程、临床证据、应用临床路径及局限性。专家组希望本临床路径共识的制订与发布能够对未来CTFR技术的临床规范化使用起到积极推动作用。【关键词】血流储备分数：冠状动脉CT血管造影；冠心病【中图分类号】R54Chinese expert consensus on the clinical pathway of coronary computed tomography angiography-derived fractional flow reserve Echocardiography and Cardiovascular Imaging Group of Chinese College ofCardiovascular Physicians,Editorail Board ofChinese Joural ofInterventional CardiologyCorresponding authors:HUO Yong,Email:huoyong @263netcn;CHEN Yun-dai,Email:cyundai@vip.163.com;LI Jian-ping,Email:13521531013@163.com[Abstract]Fractional flow reserve (FFR)is considered the "gold standard"for functionalevaluation of epicardial coronary artery stenosis,but its application in clinical practice is limited due tovarious reasons.Coronary CT angiography derived fractional flow reserve CT-FFR)obtained based oncoronary CT angiography CCTA images and advanced computational fluid dynamics and deep learningmethods can simultaneously provide anatomical and physiological information of coronary arteries.CT-FFR has became a new hotspot in clinical research and application.The use of CT-FFR in domesticclinical practice is still in the exploratory stage.This expert consensus introduces the basic principles anddiagnostic performance of CT-FFR,the workflow of CT-FFR,the clinical evidence of CT-FFR,theclinical pathway ofCT-FFR application,and the limitations of CT-FFR.The aim of this expert consensusis to promote the standardized application of CT-FFR in clinical practice.【Key words】Fractional flow reserve;Coronary CTangiography;Coronary artery disease我国心血管病现患人数约为3.3亿例，每5例死查手段为有创冠状动脉造影(invasive coronary亡中就有2例死于心血管病。冠心病推算为1139angiography,ICA)和冠状动脉CT血管造影万例且患病率呈逐年增加态势，及时准确地诊断(coronary CT angiography,CCTA)。常规ICA和和精准治疗至关重要。冠心病常用的影像检CCTA主要提供解剖信息，单凭视觉评估冠状动脉狭窄程度与心肌缺血无明确相关性]，难以从功能D0L:10.3969j.issn.1004-8812.2023.04.001学角度评价狭窄对心肌供血的影响。基金项目：国家重点研发计划项目(2021YFA1000204、冠状动脉狭窄的功能学检测方法有很多，包2016YFC1300300)通信作者：霍勇，Emal:huoyong@263.nct.cn:陈韵岱，Email:括心电图负荷试验、超声负荷试验、同位素或磁共cyundai@yp.163com;李建平，Email:13521531013@163com振负荷试验等。1993年Pj1s等3提出通过压力测(C)1994-2023 China Academic Journal Electronic Publishing House.All rights reserved.http://www.cnki.net
