Chinese Journal of New Drugs 2023,32 (4)·中成药合理应用·活血化瘀类中成药合理用药指南（上篇）《活血化瘀类中成药合理用药指南》编写专家组[摘要]中医药对血瘀证治疗和活血化瘀类药物的应用具有丰富的理论实践经验，当代活血化瘀治法的广泛应用为重大疾病防治作出了重要贡献。但活血化瘀类中成药的临床应用仍存在应用指征、疗效、作用特点、安全性信息、剂量和疗程等尚不明确的问题，由于不合理用药导致的出血等安全性问题一直受到行业关注。为向中医师、西医师、全科医生及临床药学人员提供科学合理、规范使用活血化瘀中成药的一殷原则，本指南编写组遵循循证原则，参考目前高质量临床证据，制定《活血化瘀类中成药合理用药指南》，其中上篇部分包含8项活血化瘀类中成药品种、16项推荐意见，涉及妇科、骨伤科、外科、耳鼻喉科、皮肤科、眼科。[关键词]血瘀证：活血化瘀类中成药：合理用药：指南[中图分类号]R969.3[文献标志码]A[文章编号]1003-3734(2023)04-0329-09Guidelines for rational use of proprietary chinese medicines for promotingblood circulation for removing blood stasis"Guidelines for Rational Use of Proprietary Chinese Medicines for Promoting Blood circulation andRemoving Blood Stasis"Writing Expert Group[Abstract]Chinese medicine has rich theoretical and practical experience in the treatment of blood stasisand the application of blood-activating and stasis-removing drugs.The widespread use of contemporary blood-activatingand blood-stasis treatment methods has made an important contribution to the prevention and treatment of majordiseases.However,the clinical application of blood-activating and stasis-transforming Chinese patent medicinesstill suffers from unclear application indications,efficacy,action characteristics,safety information,dose andcourse of treatment,ete.Safety issues such as bleeding caused by irrational use of drugs have been a concem in theindustry.To provide traditional Chinese medicine practitioners,Westem medicine practitioners,general practitionersand clinical pharmacists with general principles for the scientific,rational and standardized use of blood-activatingand blood-stasis-removing proprietary Chinese medicines.This guideline writing group follows the evidence-basedprinciples and makes reference to the current high-quality clinical evidence to develop the"Guidelines for RationalUse of Proprietary Chinese Medicines for Promoting Blood circulation and Removing Blood Stasis".The upper partcontains 8 varieties of blood-activating and stasis-transforming Chinese patent medicines and 16 recommendations,involving gynecology,orthopedics,surgery,otorhinolaryngology,dermatology and ophthalmology.[Key words]blood stasis syndrome;activating blood circulation and removing blood stasis class of proprietaryChinese medicines;rational use of drugs;guidelines1背景目的及意义和丰富的内涵。血瘀证已成为中医诊疗实践中的常祖国医学对瘀血证和活血化瘀治法的理论和经见症候，活血化瘀亦为常见治法，在内科、妇科、骨伤验由来已久，对活血化瘀治法积累了较系统的认识科、外科、耳鼻喉科、皮肤科、眼科等疾病应用广[基金项目]中国中医科学院科技创新工程重大攻关项日：三结合审评证鐫体系下的中药新药临床评价关键技术研究(C2021A04701)[作者简介】高蕊，女，主任医师，主要从事中药临床药理及中医内科内分决。联系电话：(010)62835651，E-mail:ruigo@126.m。[通讯作者]杨忠寺，男，主任中医师，博士生导师，主要从事中医药临床及中医心血管内科研完。联系电话：(020)36585059，Eml:yg。zhongi@163.como329中国新药杂志2023年第32卷第4期
