2023年4月1第48卷第8期②中国中药杂志Vol 48,No.8 April,2023·指南与共识·颈痛颗粒治疗神经根型颈椎病临床应用专家共识唐彬2，朱立国，魏戌，丁文元3，徐展望4，孙凯，银河，代表编制组(1.中国中医科学院望京医院，北京100102；2.广西中医药大学第一附属医院，广西南宁530022：3.河北医科大学第三医院，河北石家庄050051；4.山东中医药大学附属医院，山东济南250011)[摘要]颈痛颗粒具有活血化瘀、行气止痛之效，广泛应用于神经根型颈椎病的临床治疗。长期的临床应用和相关研究证据表明，该药在改善神经根型颈椎病引起的颈肩及上肢疼痛、发僵或窜麻、窜痛等方面有较好疗效，但该药临床应用尚缺乏具有共识性的指导意见。为更好地指导临床医生规范、合理使用颈痛颗粒治疗疾病，提高临床疗效，减少用药风险，使患者受益，特邀请来自全国的临床及方法学专家编写该共识。首先，在充分考虑专家临床经验的基础上，遵循规范的研制程序，梳理颈痛颗粒临床应用的适应证及证候特点、，优势临床症状及可能发生的不良反应。其次，对全国数名中医和西医临床一线医生开展面对面访谈和临床应用调查，系统梳理临床问题，通过名义组法达成共识形成最终的临床问题。然后，针对临床问题开展证据检索，对相关证据进行系统评价，采用国际公认的GRDE分级系统对证据进行质量评级，并再次通过名义组法达成了5项推荐意见和3项共识建议。最后，共识内容通过专家会议以及函审的方式，在全国范围内进行了征求意见和同行评议。该共识包括颈痛颗粒的临床适应证有效性、安全性证据的梳理和总结，适用于在医院及基层卫生服务机构的临床医生，可为该药的临床应用提供参考。[关键词]颈痛颗粒：神经根型颈椎病：专家共识：GRADEExpert consensus for Jingtong Granules in treatment of cervicalradiculopathy in clinical applicationTANG Bin'.2,ZHU Li-guo,WEI Xu',DING Wen-yuan',XU Zhan-wang',SUN Kai',YIN He',represented the developing group(1.Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China;2.the First Affiliated Hospital of Guangci University of Chinese Medicine,Nanning 530022,China;3.the Third Hospital of Hebei Medical University,Shijiazhuang 050051,China:4.the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan 250011,China)[Abstract]With the effects of activating blood and resolving stasis,and moving Qi to relieve pain,Jingtong Granules is widely usedin the treatment of cervical radiculopathy in China.Long-term clinical application and related evidence have shown that the prescriptionhas ideal effect in alleviating the pain in neck,shoulder,and upper limbs,stiffness or scurrying numbness,and scurrying pain causedby this disease.However,there is a lack of consensus on the clinical application of Jingtong Granules.Therefore,clinical first-lineexperts and methodology experts frm all over the country were invited to compile this expert consensus.This expert consensus isexpected to guide clinicians to use Jingtong Granules in a standardized and reasonable way,improve clinical efficacy,reducemedication risks,and benefit patients.First,according to the clinical experience of experts and the standard development procedures,the indications,syndrome characteristics,clinical advantages,and possible adverse reactions of Jingtong Granules were summarized.Then,through face-to-face interview of clinical doctors in traditional Chinese medicine and western medicine and survey of the clinical[收稿日期]2022-11-02[通信作者]·未立回，主任医师，博士生导师，研究方向为中医药防治骨与关节退行性接病，Emil:g95@un.cm:·魏戌，研究莫，博士生导师，研究方向为中医药防治骨与关节退行性疾病，E-ml:wx山.007@163.心[作者简介]唐彬，博士，主治医师，研究方向为中医药防治骨与关节退行性疾病，E-mil:15652762632@163.00m2260
