网络首发时间：2023-03-1907：0453网络首发地址：https:/kns.cnki.net/kcms/detail/13.1222.R.20230316.2124.002.html中国全科医学http/hewne.chinagpnet E-mail-agqkyx(@chinagp.net.en1·指南·共识·认知衰退老年人非药物干预临床实践指南：身体活动中国老年护理联盟，中南大学湘雅护理学院（中南大学湘雅泛海健康管理研究院），中南大学湘雅医院（国家老年疾病临床医学研究中心），北京医院（国家老年医学中心、国家老年疾病临床医学研究中心）【摘要】认知衰退是指一种或多种认知域的功能受损，多以老年人为主要发病人群。依据认知功能损害的程度，主要包括主观认知下降(SCD)、轻度认知障碍(MCI)和痴呆。SCD和MC人群具有较高的痴呆进展风险，严重影响患者生活质量，给家庭和社会造成了巨大负担。大量研究证明，身体活动是认知衰退的有效非药物干预方式之一。但是，目前认知衰退身体活动干预方案尚无统一标准，且尚无考虑中国认知衰退老年人价值观和偏好的相关身体指南，导致证据的传播与应用在一定程度上受到阻碍。本指南旨在基于现有循证证据，并考虑中国认知衰退老年人的价值观和偏好，依据推荐意见评估、制定及评价(GRADE)分级体系制订适合中国国情的《认知衰退老年人非药物干预临床实践指南：身体活动》。最终形成了针对认知衰退老年人身体活动8条推荐意见，以期能够降低认知衰退发生率，阻止或延缓认知衰退向痴呆的发生发展。【关键词】认知衰退；认知障碍；老年人；身体活动；运动；非药物干预；指南【中图分类号】R741【文献标识码】AD0I:10.12114.ssn.1007-9572.2023.0073中国老年护理联盟，中南大学湘雅护理学院（中南大学湘雅泛海健康管理研究院），中南大学湘雅医院（国家老年疾病临床医学研究中心)，等.认知衰退老年人非药物干预临床实践指南：身体活动[」」.中国全科医学，2023.China Gerontological Nursing Alliance,Xiang Ya Nursing School Xiangya Oceanwide Health Management ResearchInstitute of Central South University),Xiangya Hospital Central South University (National Clinical Research Center forGeriatric Disorders),et al.Clinical practice guideline on non-pharmacological interventions for older adults with cognitivedysfunction:physical activity [J].Chinese General Practice,2023.Clinical Practice Guideline on Non-pharmacological Interventions for Older Adults with Cognitive Dysfunction:PhysicalActivity China Gerontological Nursing Alliance,Xiang Ya Nursing School(Xiangya Oceanuide Health Management ResearchInstitute of Central South University),Xiangya Hospital Central South University (National Clinical Research Center for GeriatricDisorders),Beijing Hospital National Center for Gerontology,National Clinical Research Center for Geriatric Disorders)Writers:ZENG Xianmei,HU Mingming,FENG Hui"Xiang Ya Nursing School,Central South Unirersity,Changsha 410000,ChinaCorresponding author:FENG Hui,Professor;E-mail:feng.hui@esu.edu.cn[Abstract Cognitive dysfunction refers to the functional impairment in one or more cognitive domains,mostly occursin older adults.Cognitive dysfunction can commonly be divided into subjective cognitive decline (SCD),mild cognitiveimpairment MCI and dementia,depending on the degree of cognitive impairment.People with SCD or MCI have a higherrisk of dementia,which seriously affects their quality of life,and imposes a huge burden on families and society.Numerousstudies have demonstrated that physical activity is one effective non-pharmacological intervention for cognitive dysfunction,but there are no uniform standards for physical activity programs for cognitive dysfunction worldwide,and China still has nophysical activity guidelines based on the values and preferences ofolder adults with cognitive dysfunction,partially impeding thedissemination and application of relevant evidence.In view of this,we developed a guideline containing eight recommendationsthat is applicable in China,namely the Clinical Practice Guideline on Non-pharmacological Interventions for Older Adults
