價Check for updatesReceived:18 January 2023 Accepted:17 March 2023D0101111jebm12526GUIDELINEWILEYAcupuncture for treatment of knee osteoarthritis:A clinicalpractice guidelineXiaochao Luo123 Jiali Liu1.23 I Qianrui Li12.3.4 Jiping Zhao5 I Qiukui Hao7 ILing Zhao8 I Yemeng Chen Pengbin Yin10.11 I Ling Li123 I Fanrong Liang8Xin Sun123Chinese Evidence-Based Medicine Center,Cochrane China Center and MAGIC China Center,West China Hospital,Sichuan University.Chengdu,China2NMPAKey Laboratory for Real World Data Research and Evaluation in Hainan Chengdu.ChinaSichuan Center of Technology Innovation for Real World Data,Chengdu,ChinaDepartmentof Nuclear Medicine,West China Hospital Sichuan University.Chengdu,China5Departmentof Acupuncture and Moxibustion,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing.China6The Center of Gerontology and Geriatrics/National Clinical Research Center of Geriatrics.West China HospitalSichuan University.Chengdu China7School of RehabilitationScience,McMaster University.Hamilton,Ontario.CanadaAcupuncture and Tuina School Chengdu University of TraditionalChinese Medicine,Chengdu,ChinaNew York College of Traditional Chinese Medicine,Mineola,New York10Departmentof Orthopedics,Chinese PLAGeneral Hospital,Beijing.China11National Clinical Research Center for Or thopedics,Sports Medicine and Rehabilitation Beijing.ChinaCorrespondenceXin Sun and Ling Li.Chinese Evidence-BasedAbstractMedicine Center,Cochrane China Center andMAGIC China Center,West China Hospital,Clinical question:Is acupuncture effective in treating knee osteoarthritis(KOA)?Sichuan University,Chengdu,China.Current practice:Although increasingly used in the clinical setting,acupuncture is notEmail:sunxin@wchscu.cn:liling@wchscu.cnmentioned or weakly recommended in guidelines for the treatment of KOA.Fanrong Liang.Acupuncture and Tuina School,Chengdu University of Traditional ChineseRecommendations:We suggest acupuncture rather than no treatment in adult KOAMedicine,Chengdu,China.(weak recommendation,moderate certainty evidence),and acupuncture combinedEmail:Ifr@cdutcm.edu.cnwith nonsteroidal anti-inflammatory drugs(NSAIDs)rather than acupuncture aloneFunding informationwhen KOA symptoms are severe (weak recommendation,moderate certainty evi-National Science Fund for Distinguished Youngdence),with duration of acupuncture for 4-8 weeks depending on KOA severityScholars,Grant/Award Number:82225049:Sichuan Provincial Central Governmentand treatment response (weak recommendation,moderate certainty evidence),andGuides Local Science and Technologydiscussing with patients in shared decision-making.Development Special Project,Grant/AwardNumber:2022ZYD0127;FundamentalHow this guideline was created:This rapid recommendation was developed followingResearch Funds for the Central Public Welfarethe Making GRADE the Irresistible Choice(MAGIC)methodological framework.First,Research Institutes,Grant/Award Number:2020YJSZX-3:Innovation Team and Talentsthe clinical specialist i