中华皮肤科杂志2023年6月第56卷第6期Chin J Dematol,June2023.Vcl.56.Na6479指南与共识中国慢性诱导性荨麻疹诊治专家共识(2023)中华医学会皮肤性病学分会免疫学组通信作者：宋志强，Email:drsongzq@hotmail.com;顾恒，Email:guheng(@aliyun.com【摘要】慢性诱导性荨麻疹是一组由特定诱因诱发、以风团和域血管性水肿为主要临床表现的慢性荨麻疹，可伴有瘙痒、刺痛、烧灼、疼痛等不适症状。该病临床表现异质性大，病情迁延反复，对患者生活质量影响较大。为提升我国临床医生对该病的认识，规范疾病诊治行为，中华医学会皮肤性病学分会免疫学组基于近年来国内外关于慢性诱导性荨麻疹诊断和治疗的临床研究进展，通过德尔菲法广泛征询专家意见，并经相关专家多轮讨论，最终形成本共识。【关键词】荨麻疹；慢性诱导性荨麻疹；皮肤划痕征；冷接触性荨麻疹；胆碱能性荨麻疹；诊断；治疗：专家共识D0I:10.35541/cjd.20220819Expert consensus on diagnosis and treatment of chronic inducible urticaria in China(2023)Immunology Group,Chinese Society of DermatologyCorresponding authors:Song Zhiqiang,Emaik drsongzq@hotmail com:Gu Heng,Email:guheng @aliyun.com[Abstract]Chronic inducible urticaria is a group of chronic urticaria induced by specific triggers,with wheal and/or angioedema as main clinical manifestations,which may be accompanied by itching,tingling.burning sensation,pain and other unpleasant symptoms.This group of diseases are characterizedby highly heterogeneous clinical manifestations,long courses,and recurrent symptoms,which have a greatimpact on the quality of life of patients.Based on the progress in Chinese and interational clinical studieson the diagnosis and treatment of chronic inducible urticaria in recent years,the Immunology Group ofChinese Society of Dermatology extensively consulted experts through the Delphi method,and finallydeveloped this consensus after several rounds of discussion among relevant experts,in order to improveclinicians'understanding of this group of diseases and standardize their diagnosis and treatment.[Key words]Urticaria;Chronic inducible urticaria;Symptomatic dermographism;Cold contacturticaria;Cholinergic urticaria;Diagnosis;Treatment;Expert consensusD0l:10.35541/ejd.20220819慢性荨麻疹分为慢性自发性荨麻疹(chronic识。为提升临床医生对CndU的认识，规范CndUspontaneous urticaria,CSU)和慢性诱导性荨麻疹的诊治行为，中华医学会皮肤性病学分会免疫学组(chronic inducible urticaria,CIndU)。CndU是一组在总结国内外CIndU诊疗研究进展的基础上，基于由特定诱因（冷、热、运动、压力、阳光、振动、水等）德尔菲(Delphi)专家问卷咨询法广泛征询专家意诱发、以风团和/或血管性水肿为主要临床表现的见，并经相关专家多轮讨论，最终形成了本共识。荨麻疹。相比于CSU,CIndU发生的诱因明确，但其病因不明，发病机制复杂。CndU存在多个类型一、流行病学和更多细分亚型，临床表现异质性强，病情迁延反复，对患者生活质量影响较大。目前关于我国人群cndU的流行病学研究报一直以来国内对该疾病关注度偏低，尤其是广道较少。2014年一项基于我国医院就诊患者群体大基层皮肤科医生对其缺乏全面深入的了解，诊治的多中心临床流行病学研究结果显示，CIndU占慢行为不够规范。目前全世界仅欧洲过敏与临床免性荨麻疹的31.9%（其中物理性荨麻疹占29.3%，非疫学会曾发布过CIndU的共识，但已6年未更物理性荨麻疹占2.6%)，最常见类型依次为皮肤划新四。我国尚未有针对CndU的诊疗指南或共痕征（也称人工荨麻疹，20.9%）、冷接触性荨麻疹
