ARTICLE IN PRESSJOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGYv0L.■,No.■.20232023 BY THE AMERICAN COLLEGE OF CARDIOLOGY FOUNDATIONPUBLISHED BY ELSEVIEREXPERT CONSENSUS DECISION PATHWAY2023 ACC Expert ConsensusDecision Pathway onManagement of Heart FailureWith Preserved Ejection FractionA Report of the American College of Cardiology Solution Set Oversight CommitteeWritingMichelle M.Kittleson,MD,PuD,FACC,ChairAnita Deswal,MD,MPH,FACCCommitteeGurusher S.Panjrath,MBBS,FACC,Vice ChairDave L.Dixon,PHARMD,FACCJames L.Januzzi JR,MD,FACCKaushik Amancherla,MDClyde W.Yancy,MD,MSc,MACCLeslie L.Davis,PHD,ANP-BC,FAAN.FACCSolution SetNicole M.Bhave,MD,FACC,ChairDharam J.Kumbhani,MD,SM,FACCOversightGurusher S.Panjrath,MBBS,FACCCommitteeNiti R.Aggarwal,MD,FACCBarbara Wiggins,PHARMD,FACCKatie Bates,ARNP,DNPDavid E.Winchester,MD,MS,FACCBiykem Bozkurt,MD,PuD,FACCMegan Coylewright,MD,MPH,FACC,Ex OfficioJohn P.Erwin m,MD,FACCTABLE OF CONTENTSPREFACE22.METH0Ds.....................41.NTR0 DUCTION.....33.ASSUMPTIONS AND DEFINITIONS....................51.1.The Scope of the Problem........................33.1.General Clinical Assumptions.....................51.2.Challenges in the Diagnosis of HFpEF...............33.2.Definitions.....................................513 Challenges in the Treatment of HFpEF..............44.PATHWAYSUMMARYGRAPHIC......................51.4 Specific Challenges in the Management of WomenWith HFpEF4Figure 1.Approach to HFpEF........................6This document was approved by the American College of Cardiology Clinical Policy Approval Committee in March 2023.The American College of Cardiology requests that this document be cited as follows:Kittleson MM,Panjrath GS,Amancherla K,Davis LL,Deswal A,Dixon DL,Januzzi JL Jr,Yancy CW.2023 ACC expert consensus decision pathway on management of heart failure with preserved ejection fraction:areport of the American College of Cardiology Solution Set Oversight Committee.J Am Coll Cardiol.Published online April 19,2023.https://doi.org/1o.1016/1jhcc.2023.03.393.Copies:This document is available on the website of the American College of Cardiology (www.acc.org).For copies of this document,please contactElsevier Inc.Reprint Department via fax (212-633-3820)or e-mail (reprintselsevier.com).Permissions:Multiple copies,modification,alteration,enhancement,and/or distribution of this document are not permitted without the expresspermission of the American College of Cardiology.Requests may be completed online via the Elsevier site (htt ps://www.elsevier.com/about/policies/copyright/permissions).1ssN07351097/536.00https://doi.org/10.1016/j.jacc2023.03.393