ReviewEuropean Association of Nuclear Medicine(EANM)Focus 4consensus recommendations:molecular imaging andtherapy in haematological tumoursCristina Nanni"Carsten Kobe,Bettina Baeler,Christian Baues,Ronald Boellard Peter Borchmann,Andreas Buck,Irene Buvat,Bjorn Chapuy,Bruce D Cheson,Robert Chrzan,Ann-Segolene Cottereau,Ulrich Duhrsen,Live Eikenes,Martin Hutchings,Wojciech Jurczak,Francoise Kraeber-Bodere,Egesta Lopci Stefano Luminari,Steven MacLennan,N George Mikhoeel,Marcel Nijland,Paula Rodriguez-Otero,Giorgio Treglia,Nadia Withofs,Elena Zamagni Pier Luigi Zinzani Josee M Zijlstra,Ken Herrmann*,Jolanta Kunikowska*Given the paucity of high-certainty evidence,and differences in opinion on the use of nuclear medicine for LancetHaematal 2023hematological malignancies,we embarked on a consensus process involving key experts in this area.We aimed to10:e367-81assess consensus within a panel of experts on issues related to patient eligibility,imaging techniques,staging and*Contributed equallyresponse assessment,follow-up,and treatment decision-making,and to provide interim guidance by our expert Medicina Nudeareconsensus.We used a three-stage consensus process.First,we systematically reviewed and appraised the quality of(C Nanni MD)andIstitutodiexisting evidence.Second,we generated a list of 153 statements based on the literature review to be agreed or disagreedEmatologia'Seragnoli"(E Zamagni MD.with,with an additional statement added after the first round.Third,the 154 statements were scored by a panel ofProf PL Zinzani MD).IRCCS26 experts purposively sampled from authors of published research on haematological tumours on a 1 (stronglyAzienda ospedaliero-disagree)to 9(strongly agree)Likert scale in a two-round electronic Delphi review.The RAND and University ofUniversitaria di Bologna,California Los Angeles appropriateness method was used for analysis.Between one and 14 systematic reviews wereBologna,Italy:DipartimentodiMedicina Specialistica.identified on each topic.All were rated as low to moderate quality.After two rounds of voting,there was consensus onDiagnosticae Sperimentale139 (90%)of 154 of the statements.There was consensus on most statements concerning the use of PET in non-Universita di Bologna,Hodgkin and Hodgkin lymphoma.In multiple myeloma,more studies are required to define the optimal sequence forBologna,Italy (E Zamagni,Prof PL Zinzani);Department oftreatment assessment.Furthermore,nuclear medicine physicians and haematologists are awaitingconsistent literatureNuclear Medicine,Faculty ofto introduce volumetric parameters,artificial intelligence,machine learning,and radiomics into routine practice.Medicine and UniversityHospital Cologne,UniversityofIntroductionWithin our overarching aim,our objectives were toCologne,Cologne,GermanyThe use of nuclear medicine techniques has changed the describe the extent of consensus on the use of [18F]DiagnosticandInterventionalstandard of care in many clinical situations relating tofuorodeoxyglucose
