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價Check for updatesPERITONEALDIALYSISSpecial Series/GuidelinesINTERNATIONALPeritoneal Dialysis International1-19ISPD Catheter-related InfectionThe Author(s)2023©0©Recommendations:2023 UpdateArticle reuse guidelines:sagepub.com/journals-permissionsDOt10.1177/08%8608231172740jourmals.sagepub.com/home/ptdS SageKai Ming Chow2,Philip Kam-Tao Li2,Yeoungjee Cho34,Ali Abu-Alfa5.5,Sunita Bavanandan7,Edwina A Brown,Brett Cullis,Dawn Edwards1,Isabelle Ethier2Helen Hurst'3,Yasuhiko Ito4,Thyago Proenca de Moraes5,Johann Morelle's,Naomi Runnegar7,Anjali Saxenal8,19,7Simon Wai-Yin So20,Na Tian21 and David W JohnsonAbstractPeritoneal dialysis(PD)catheter-related infections are important risk factors for catheter loss and peritonitis.The 2023updated recommendations have revised and clarified definitions and classifications of exit site infection and tunnelinfection.A new target for the overall exit site infection rate should be no more than 0.40 episodes per year at risk.Therecommendation about topical antibiotic cream or ointment to catheter exit site has been downgraded.New recom-mendations include clarified suggestion of exit site dressing cover and updated antibiotic treatment duration withemphasis on early clinical monitoring to ascertain duration of therapy.In addition to catheter removal and reinsertion,other catheter interventions including external cuff removal or shaving,and exit site relocation are suggested.KeywordsAntibacterial agents,antibiotic prophylaxis,catheter-related infections,exit site infection,ISPD guideline,peritonealdialysis,prevention,treatment outcomeDepartment of Medicine and Therapeutics,Prince of Wales Hospital.Department of Nephrology and Rheumatology.Aichi MedicalThe Chinese University of Hong Kong.Hong KongUniversity,Nagakute,Japan2Carol Richard Yu Peritoneal Dialysis Research Centre,DepartmentI5Programa de Pos-Graduacao em Ciencias da Saude.Pontificiaof Medicine and Therapeutics,The Chinese University of Hong Kong.Universidade Catolica do Parana,Curitiba,BrazilHong KongDivision ofNephroloy,Cliniquesuniversitaires Saint-Luc,Brussels,BelgiumBAustralasian Kidney Trials Network,University of Queensland,17Infectious Management Services,Princess Alexandra Hospital,Brisbane,AustraliaUniversity of Queensland,Brisbane,AustraliaDepartment of Nephrology.Princess Alexandra Hospital,Brisbane,Department of Medicine.Division of Nephrology.Stanford University.AustraliaCA,USADivision of Nephrology and Hypertension,American University of1Department of Medicine.Division of Nephrology.Santa Clara ValleyBeirut,LebanonMedical Center,San Jose,CA,USASection of Nephrology.Yale School of Medicine.New Haven.CT.USA2Department of Pharmacy.Alice Ho Miu Ling Nethersole Hospital.Tai7Department of Nephrology.Hospital Kua Lumpur,MalaysiaPo,Hong KongImperial College Renal and Transplant Centre,Imperial College NHS2Department of Nephrology.General Hospital of NingXia MedicalTrust,London,UKUniversity,Yinchuan,ChinaDepartent of Nephrology and Child Health.University