Advance PublicationCirculation JournalJCS GUIDELINESdoi:10.1253/circj.CJ22-0779JCS/CVIT/JCC 2023 Guideline Focused Update onDiagnosis and Treatment of Vasospastic Angina(Coronary Spastic Angina)andCoronary Microvascular DysfunctionSeiji Hokimoto:Koichi Kaikita:Satoshi Yasuda:Kenichi Tsujita:Masaharu Ishihara:Tetsuya Matoba;Yasushi Matsuzawa;Yoshiaki Mitsutake;Yoshihide Mitani;Toyoaki Murohara;Takashi Noda;Koichi Node;Teruo Noguchi;Hiroshi Suzuki;Jun Takahashi;Yasuhiko Tanabe;Atsushi Tanaka*;Nobuhiro Tanaka;Hiroki Teragawa;Takanori Yasu;Michihiro Yoshimura;Yasuhide Asaumi;Shigeo Godo;Hiroki Ikenaga;Takahiro Imanaka;Kohei Ishibashi;Masanobu Ishii;Takayuki Ishihara;Yunosuke Matsuura;Hiroyuki Miura;Yasuhiro Nakano;Takayuki Ogawa;Takashi Shiroto;Hirofumi Soejima;Ryu Takagi;Akihito Tanaka;Atsushi Tanaka#;Akira Taruya;Etsuko Tsuda;Kohei Wakabayashi;Kensuke Yokoi;Toru Minamino;Yoshihisa Nakagawa;Shozo Sueda;Hiroaki Shimokawa;Hisao Ogawaon behalf of the Japanese Circulation Society and Japanese Association of Cardiovascular Interventionand Therapeutics and Japanese College of Cardiology Joint Working GroupTable of ContentsPre时C22.Phammacological Coronary Spasm Provocation Test.......21I.New Disease Concepts Related to Coronary3.VUS,OCTa4a…24Sp阳…34.Coronary Angioscopy...265.CT,MRI,Nuclear Medicine Examinations..............272.INOCA.....6.Vascular Endothelial Function Test and Vascularactiyity…30Il.New Insights Into Pathogenesis.147.Invasive Coronary Physiological Testing.......31IV.New Insights Into Treatment..........................341.Genetic Factors Pathogenesis..142.ALDH2 Polymorphism and Alcohol Metabolism..141.Daity Life Management........342.Pharmacotherapy.343.Coronary Microvascular Spasm......153.Nonphammacotherapy....…364.Coronary Spasm After Drug-Eluting StentV.Providing Information to Citizens andImplantation.....17Pgtients...395.Pediatric Disease,Coronary Sequelae in KawasakiDisease and Vasospastic Angina...............19References40II.New Insights Into Diagnosis20Appendix 1........531.Diagnostic Criteria....20Appendix 2.....54J-STAGE Advance Publication released online March 10,2023This document is an English version of the JCS/CVIT/JCC 2023 Guideline Focused Update on Diagnosis and Treatment ofVasospastic Angina(Coronary Spastic Angina)and Coronary Microvascular Dysfunction reported at the 87th Annual ScientificMeeting of Japanese Circulation Society,2023.(Website:https://www.j-circ.or.jp/cms/wp-content/uploads/2023/03/JCS2023_hokimoto.pdf).◆,Separate individuals..Refer to Appendix 1 for the details of members.JCS Joint Working Groups:The Japanese Circulation Society,Japanese College of Cardiology,Japanese Association ofCardiovascular Intervention and Therapeutics,Japanese Society of Pediatric Cardiology and Cardiac Surgery,Japanese HeartRhythm Society,The Japanese Association of Cardiac Rehabilitation,The Japanese Coronary Association,Japanese Associationof CardioangioscopyMailing address:Guideline Committee of the Japanese Circulation So