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Advance PublicationCirculation JournalJCS GUIDELINESdoi:10.1253/circj.CJ22-0696JCS 2023 Guideline on the Diagnosis andTreatment of MyocarditisToshiyuki Nagai;Takayuki Inomata;Takashi Kohno;Takuma Sato;Atsushi Tada;Toru Kubo;Kazufumi Nakamura;Noriko Oyama-Manabe;Yoshihiko Ikeda;Takeo Fujino;Yasuhide Asaumi;Takahiro Okumura;Toshiyuki Yano;Kazuko Tajiri;Hiroyuki Matsuura;Yuichi Baba;Haruki Sunami;Shingo Tsujinaga;Yasutoshi Ota;Keiko Ohta-Ogo;Yusuke Ishikawa;Hideo Matama;Nobutaka Nagano;Kimi Sato;Kazushi Yasuda;Yasushi Sakata;Koichiro Kuwahara;Tohru Minamino;Minoru Ono;Toshihisa Anzaion behalf of the Japanese Circulation Society Joint Working GroupTable of ContentsPreamble…2IV.Treatment and Management.....341.Process of Preparation.31.Basic Treatment and Management................................34I.Introduction......462.Immunosuppressive Therapy.421.Definition and Classification.....63.Immunomodulatory/Antiviral Therapy..................45V.Progno0…463.Pathophysiology181.Acute Myocarditis....462.Chronic Active Myocarditis/Chronic Inflammatoryl.Diagn0 ww…11Cadi0my0 athy…471.Signs and Symptoms....11VI.Diagnosis and Treatment of Specific2.Electrocardiography.12Types of Myocarditis.................473.Bl00 d Tests161.Eosinophilic Myocarditis.474.Echocardiography..192.Giant Cell Myocarditis......505.Cardiac MRl.…203.Myocarditis Associated With Autoimmune Diseases......546.Cardiac Nuclear Imaging.234.Drug-Induced Myocarditis.567.Endomyocardial Biopsy,Cardiac Catheterization...........235.Myocarditis in Neonates.....60Diagnostic Algorithm............326.Myocarditis in Children..m621.Acute Myocarditis....32References..............:662.Chronic Active Myocarditis and ChronicAppendix 1..........478Inflammatory Cardiomyopathy33Appendix 2......78J-STAGE Advance Publication released online March 10,2023This document is an English version of JCS 2023 Guideline on the Diagnosis and Treatment of Myocarditis reported at the 87thAnnual Scientific Meeting of the Japanese Circulation Society in 2023.(Website:https://www.j-circ.or.jp/cms/wp-content/uploads/2023/03/JCS2023_nagai.pdf)Refer to Appendix 1 for the details of members.JCS Joint Working Groups:The Japanese Circulation Society:The Japanese College of Cardiology:The Japanese Heart FailureSociety:The Japanese Society of Pediatric Cardiology and Cardiac SurgeryMailing address:Guideline Committee of the Japanese Circulation Society,6th Floor,Uchikanda Central Building.1-18-13Uchikanda,Chiyoda-ku,Tokyo 101-0047,Japan.email:jcsGL@j-circ.or.jpAll rights are reserved to the Japanese Circulation Society.For permissions,please email:cj@j-circ.or.jpc©O⊙ISSN-1346-9843BY NC NO