價Check for updatesReceived:14 October 2022 Accepted:14 October 2022D0l10.3322/ca3c217632023ARTICLECancer statistics,2023Rebecca L.Siegel MPH Kimberly D.Miller MPHNikita Sandeep Wagle MBBS,MHA,PhD Ahmedin Jemal DVM,PhDSurveillance and Health Equity ScienceAmerican Cancer Society,Atlanta,GeorgiaAbstractUSAEach year,the American Cancer Society estimates the numbers of new cancer casesCorrespondenceand deaths in the United States and compiles the most recent data on population-Rebecca L Siegel,Surveillance Research.based cancer occurrence and outcomes using incidence data collected by centralAmerican Cancer Society.3380 ChastainMeadows Par kway NW.Suite 200,Kennesaw,cancer registries and mortality data collected by the National Center for HealthGA30144U5AStatistics.In 2023,1,958,310 new cancer cases and 609,820 cancer deaths areEmail:rebecca.siegel@cancer.orgprojected to occur in the United States.Cancer incidence increased for prostatecancer by 3%annually from 2014 through 2019 after two decades of decline,translating to an additional 99,000 new cases;otherwise,however,incidence trendswere more favorable in men compared to women.For example,lung cancer inwomen decreased at one half the pace of men(1.1%vs.2.6%annually)from 2015through 2019,and breast and uterine corpus cancers continued to increase,as didliver cancer and melanoma,both of which stabilized in men aged 50 years and olderand declined in younger men.However,a 65%drop in cervical cancer incidenceduring 2012 through 2019 among women in their early 20s,the first cohort toreceive the human papillomavirus vaccine,foreshadows steep reductions in the5burden of human papillomavirus-associated cancers,the majority of which occur inwomen.Despite the pandemic,and in contrast with other leading causes of death,the cancer death rate continued to decline from 2019 to 2020(by 1.5%),contrib-uting to a 33%overall reduction since 1991 and an estimated 3.8 million deathsaverted.This progress increasingly reflects advances in treatment,which areparticularly evident in the rapid declines in mortality (approximately 2%annuallyduring 2016 through 2020)for leukemia,melanoma,and kidney cancer,despitestable/increasing incidence,and accelerated declines for lung cancer.In summary,although cancer mortality rates continue to decline,future progress may beattenuated by rising incidence for breast,prostate,and uterine corpus cancers,which also happen to have the largest racial disparities in mortality.KEYWORDScancer cases,cancer statistics,death rates,incidence,mortalityThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License,which permits use and distribution in anymedium,provided the original work is properly cited,the use is non-commercial and no modifications or adaptations are made.2023 The Authors.CA:A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society.CA Cancer J Clin.2023:73:17-48.wileyonlinelibrary.com/j
