）Check for updatesJonathan Wadsley ORCID iD:0000-0002-1499-1277Consensus statement on the management ofincidentally discovered FDG avidthyroid nodules in patients being investigated for other cancersAuthorsProfessor J Wadsley Weston Park Cancer Centre,SheffieldProfessor SP Balasubramanian Sheffield Teaching Hospitals,SheffieldDr G Madani Imperial College Healthcare NHS Trust,LondonMrs J Munday Queen Alexandra Hospital,PortsmouthDr T Roques Norfolk and Norwich HospitalDr CW Rowe University of Newcastle,AustraliaDr P Touska Guy's and St Thomas'Hospital,LondonProfessor K Boelaert University of BirminghamCorresponding AuthorProf Jonathan Wadsley,Weston Park Cancer Centre,SheffieldWeston Park Cancer,Centre,Whitham Rd,Sheffield S10 2SJionathan.wadsley1@nhs.netAbstractWith the widespread use of 18F-fluorodeoxyglucose positron emission tomography (FDGPET/CT)in the investigation and staging of cancers,incidental discovery of FDG-avidthyroid nodules is becoming increasingly common,with a reported incidence in the range1-4%of FDG PET/CT scans.The risk of malignancy in an incidentally discovered FDG avid thyroid nodule is not cleardue to selection bias in reported retrospective series but is likely to be less than 15%.Even in cases where the nodule is found to be malignant,the majority will bedifferentiated thyroid cancers with an excellent prognosis even without treatment.If,due to index cancer diagnosis,age and co-morbidities,it is unlikely that the patientwill survive 5 years,further investigation of an incidental FDG avid thyroid nodule isunlikely to be warranted.We provide a consensus statement on the circumstances in which further investigation ofFDG avid thyroid nodules with ultrasound and fine needle aspiration might beappropriate.Key wordsFDG PETThyroid incidentalomaPrognosisIntroductionOwing to the widespread use of 18F-fluorodeoxyglucose positron emission tomography(FDG PET/CT)in the investigation and staging of cancers,incidental discovery of FDG-avid thyroid nodules (thyroid incidentaloma(TI))is becoming an increasingly commonphenomenon.It is now typical for specialist thyroid cancer multidisciplinary team(MDT)meetings to receive regular referrals of such cases.The following multicenter multidisciplinary consensus statement seeks to provideguidance to clinicians involved with the care of these patients regarding when furtherinvestigation of TI is warranted,and,perhaps more importantly,when it is not requiredA group of opinion leaders in Oncology,Endocrine Surgery,Head and Neck Radiologyand Endocrinology came together to consider whether imaging can be reduced and a lessinvasive approach adopted to FDG avid nodules in patients with a very poor prognosisThis article has been accepted for publication and undergone full peer review buthas not been through the copyediting,typesetting,pagination and proofreadingprocess,which may lead to differences between this version and the Version ofRecord.Please cite this article as doi:10.1111/cen.14905This arti
